PUMA, alpha (p53 Upregulated Modulator of Apoptosis)
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Catalog numberGEN603410
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PricePlease ask
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Size100ul
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Also known asPUMA, alpha
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Other namesPUMA alpha; Bcl-2-binding component 3; bcl-2-binding component 3; JFY-1; p53 up-regulated modulator of apoptosis; BCL2 binding component 3; JFY-1; p53 up-regulated modulator of apoptosis
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CategoryAntibodies
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SubcategoryMnoclonal antibodies
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Gene nameBBC3; BBC3; JFY1; PUMA; FLJ42994; PUMA
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Gene name synonimsBBC3; BBC3; JFY1; PUMA; FLJ42994; PUMA
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Other gene namesBBC3; BBC3; JFY1; PUMA; FLJ42994; PUMA
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ClonalityMonoclonal
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Immunoglobulin isotypeIgG
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Clone6k335
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Host organismRabbit (Oryctolagus cuniculus)
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Source organismHuman (Homo sapiens)
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Species reactivityHuman (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivityRecognizes human PUMA. Predicted to detect both isoforms based on sequence analysis. The isoform B is ~18kD and isoform A is ~24kD. Isoform B is primarily recognized on the western blot gel.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification methodSupernatant
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Form AppearanceSupplied as a liquid in 50mM Tris-glycine, pH 7.4, 0.15 sodium chloride, 0.05% BSA, 0.01% sodium azide, 40% glycerol.
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ConcentrationN/A
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Storage and shippingStore the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested applicationsWestern Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS)
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DescriptionThe PUMA, alpha (p53 Upregulated Modulator of Apoptosis) is a α- or alpha protein sometimes glycoprotein present in blood. This 1 is suited for programmed cell-death studies.
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Gene target
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Gene symbolBBC3, HCAR2
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Short namePUMA, alpha (p53 Upregulated Modulator of Apoptosis)
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Techniqueapoptosis, apoptosis pathway
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Alternative nameAnti-PUMA, alpha (p53 Upregulated Modulator of Apoptosis)
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Alternative techniquecelldeath
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Gene info
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Identity
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Gene
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Long gene nameBCL2 binding component 3
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2002-07-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- BCL2 homology region 3 (BH3) only
- MicroRNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namehydroxycarboxylic acid receptor 2
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Synonyms gene
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Synonyms gene name
- G protein-coupled receptor 109A
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-04-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Hydroxycarboxylic acid receptors
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VEGA ID