Rabbit polyclonal-Anti-Tumor Necrosis Factor Related Apoptosis Inducing Ligand (TRAIL)-20ug

• Catalog number
  PAA139Ra01-20ug
• Price
  Please ask
• Size
  20ug

• Organism Species
  Rattus norvegicus (Rat)
• Source
  Polyclonal antibody preparation
• Purification
  Antigen-specific affinity chromatography followed by Protein A affinity chromatography
• Buffer Formulation
  0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
• Item Name
  Tumor Necrosis Factor Related Apoptosis Inducing Ligand
• Immunogen
  RPA139Ra01-Recombinant Tumor Necrosis Factor Related Apoptosis Inducing Ligand (TRAIL)
• Image number
  6
• Species reactivity
  Human,Rat
• Sequence of immunogen
  TRAIL (Pro115~Ala287)
• Aplication
  WB,IHC
• Clonality
  Rabbit polyclonal
• Concentration
  500ug/ml
• Alternative Names
  CD253; TNFSF10; APO2L; Apo2-L; TL2; TRAIL; Tumor Necrosis Factor Ligand Superfamily Member 10; Apo-2 Ligand
• Applicable Secondary Antibody
  SAA544Rb59, SAA544Rb58, SAA544Rb57, SAA544Rb18, SAA544Rb19
• Manual link
• Delivery condition
  4℃ with ice bags
• Storage instructions
  Avoid repeated freeze/thaw cycles. Store at 4 ℃ for frequent use. Aliquot and store at -20℃ for 12 months.
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. This 1 is suited for programmed cell-death studies. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by Cloud Clone Corp. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cloud Clone Corp adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus

• Gene target
  Tumor   Necrosis   Factor   Related   Ligand   TRAIL   20ug  
• Gene symbol
  TNFSF10, TNFRSF10B
• Short name
  Rabbit polyclonal-Anti-Tumor Necrosis Factor Apoptosis Ligand (TRAIL)-20ug
• Technique
  Polyclonal, apoptosis, Rabbit, anti-, anti, antibody to, antibodies, apoptosis pathway, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Host
  Rabbit, Rabbits
• Alternative name
  production species: rabbit polyclonal-Antibody toTumor Necrosis Factor Related programmed cellular destruction Inducing Ligand (TRAIL)-20ug
• Alternative technique
  polyclonals, celldeath, rabbit-anti, antibodies
• Tissue
  tumor

Gene info

• Identity
  HGNC:11925
• Gene
  TNFSF10
• Long gene name
  TNF superfamily member 10
• Synonyms gene name
  • tumor necrosis factor (ligand) superfamily, member 10
• Synonyms
  • TRAIL
  • Apo-2L
  • TL2
  • CD253
• GenBank acession
  • U37518
• Locus
  3q26
• Discovery year
  1998-12-04
• Pubmed identfication
  • 8777713
  • 8663110
• Classification
  • CD molecules
  • Tumor necrosis factor superfamily
• VEGA ID
  OTTHUMG00000156917

Gene info

• Identity
  HGNC:11905
• Gene
  TNFRSF10B
• Long gene name
  TNF receptor superfamily member 10b
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 10b
• Synonyms
  • DR5
  • KILLER
  • TRICK2A
  • TRAIL-R2
  • TRICKB
  • CD262
  • TRAILR2
• GenBank acession
  • AF012628
• Locus
  8p21.3
• Discovery year
  1998-12-04
• Entrez gene record
  8795
• Pubmed identfication
  • 9285725
  • 9311998
• RefSeq identity
  • NM_147187
• Classification
  • Tumor necrosis factor receptor superfamily
  • CD molecules
• VEGA ID
  OTTHUMG00000097826

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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