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Alternative name1
Anti-Goat Polyclonal to Human LEPR / Leptin Receptor
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Alternative name2
Caprine PAb to Human LEPR / Leptin Receptor
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Alternative name3
Caprinae Polyclonal to Homo sapiens LEPR / Leptin Receptor
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Alternative name4
LEPR / Leptin Receptor
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Alternative name5
Anti-LEPR / Leptin Receptor Antibody (Internal) IHC-plus; LEPR; CD295 antigen; HuB219; LEP-R; OB receptor; LEPRD; OB-R; OBR; CD295; DB; Leptin receptor; Human LEPR; Leptin Receptor
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Other names
leptin receptor isoform 1; Leptin receptor; leptin receptor; huB219; OB receptor; leptin receptor; HuB219; OB receptor; OB-R; CD_antigen: CD295
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Gene name
LEPR
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Gene name synonims
N/A
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Other gene names
LEPR; LEPR; OBR; OB-R; CD295; LEP-R; LEPRD; DB; OBR; LEP-R; OB-R
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Category
Antibodies
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Clonality
Polyclonal
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Immunoglobulin isotype
N/A
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Clone
Polyclonal antibody
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Host organism
Goat
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Species reactivity
Gorilla, Human Predicted Reactivity: Monkey, Dog, Horse (at least 90% immunogen sequence identity)
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Specificity and cross reactivity
Human LEPR / Leptin Receptor. This antibody is expected to recognise all three reported isoforms (NP_002294.2; NP_001003679.1; NP_001003680.1).
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Purification method
Immunoaffinity Purified
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Form Appearance
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
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Concentration
0.5 mg/ml
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Storage and shipping
For optimal long term storage, productone should be kept at -20 degrees Celsius. Minimize freezing and thawing.
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Tested for
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
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Description
productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
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Advisory
In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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Properties
If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Latin name
Capra aegagrus hircus
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Gene
Human or mouse Leptin (from Greek λεπτός leptos, "thin") the "satiety hormone", is a hormone made by adipose cells that helps to regulate energy balance by inhibiting hunger. Leptin is opposed by the actions of the hormone ghrelin, the "hunger hormone". Both hormones act on receptors in the arcuate nucleus of the hypothalamus to regulate appetite to achieve energy homeostasis. ELISA kits and peptides and antibodies are available.
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Group
Polyclonals and antibodies
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About
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
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Additional description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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French translation
anticorps
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Gene target
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Gene symbol
LEPR
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Short name
Goat Polyclonal LEPR / Leptin Receptor Antibody
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Technique
Polyclonal, Antibody, Goat, antibodies against human proteins, antibodies for, goats, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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Host
Goat, The goat polyclonal antibodies are directed against human genes or rabbit or mouse IgGs (H +L) chain primary antibodies and conjugated for detection. It are very good secondary antibodies that are affinity purified and have a good affinity themselves too. Often KLH is coupled to the antigen so anti KLH can be present in the vial.
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Species
Human, Goats, Humans
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Alternative name
caprine polyclonal to H. sapiens leptin receptor / Leptin Receptor (antibody to-)
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Alternative technique
polyclonals, antibodies, caprine
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Alternative to gene target
leptin receptor, CD295 and LEP-R and LEPRD and OB-R and OBR, LEPR and IDBG-99469 and ENSG00000116678 and 3953, identical protein binding, Extracellular, Lepr and IDBG-167734 and ENSMUSG00000057722 and 16847, LEPR and IDBG-638266 and ENSBTAG00000005910 and 497205,785813
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