Eosinophil Peroxidase

• Catalog number
  GEN438346
• Price
  Please ask
• Size
  100ug

• Also known as
  Eosinophil Peroxidase
• Other names
  eosinophil peroxidase preproprotein; Eosinophil peroxidase; eosinophil peroxidase; eosinophil peroxidase; N/A
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  EPX
• Gene name synonims
  N/A
• Other gene names
  EPX; EPX; EPO; EPP; EPX-PEN; EPER; EPO; EPP; EPO
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG1, kappa
• Clone
  AHE-1
• Host organism
  Mouse (Mus musculus)
• Species reactivity
  Human (Homo sapiens).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Peripheral blood granulocytes are classified into neutrophils, basophils and eosinophils according to the staining characteristics of their cytoplasmic granules. Granule proteins are released by physiologic and pharmacologic stimuli and play important roles in both normal and pathological host immune responses. Eosinophil major basic protein and eosinophil peroxidase (EPX) are granule proteins specific to the eosinophil. AHE-1 recognizes human EPX, a granule protein specific to eosinophils. It does not cross-react with eosinophil major basic protein, elastase, cathepsin G, esterase N, thrombin, plasmin, kallikrein, lactoferrin, or transferrin. This MAb stains eosinophils only and does not stain other peripheral blood cells, including platelets, neutrophils, monocytes, lymphocytes or red blood cells. Human EPX gene product can form a tetramer of two light chains and two heavy chains. Other peroxidase family members include myeloperoxidase (MPO), lactoperoxidase (LPO), and thyroid peroxidase (TPO).; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  N/A
• Form Appearance
  N/A
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
• Tested applications
  ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistology (IH)
• Conjugate
  Peroxidases with EC number 1.11.1.x are catalyzing the reaction of ROOR' + electron donor (2 e−) + 2H+ → ROH + R'OH

• Gene target
  Eosinophil  
• Gene symbol
  EGOT, EPX
• Short name
  Eosinophil
• Label
  peroxidase
• Alternative name
  Anti-Eosinophil Peroxidase

Gene info

• Identity
  HGNC:37129
• Gene
  EGOT
• Long gene name
  eosinophil granule ontogeny transcript
• Synonyms gene name
  • eosinophil granule ontogeny transcript (non-protein coding)
• Synonyms
  • EGO
  • NCRNA00190
• Synonyms name
  • eosinophil granule ontogeny
  • non-protein coding RNA 190
• GenBank acession
  • BC039547
• Locus
  3p26.1
• Discovery year
  2009-07-28
• Entrez gene record
  100126791
• Pubmed identfication
  • 17351112
  • 22303364
• RefSeq identity
  • NR_004428
• Classification
  • Long non-coding RNAs with non-systematic symbols
• VEGA ID
  OTTHUMG00000156235

Gene info

• Identity
  HGNC:3423
• Gene
  EPX
• Long gene name
  eosinophil peroxidase
• Synonyms
  • EPO
  • EPP
  • EPX-PEN
• GenBank acession
  • M26515
• Locus
  17q22
• Discovery year
  1998-11-24
• Entrez gene record
  8288
• Pubmed identfication
  • 2550461
  • 2541222
• RefSeq identity
  • NM_000502
• VEGA ID
  OTTHUMG00000178802

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