Eosinophil Peroxidase

• Catalog number
  MBS438229
• Price
  Please ask
• Size
  5x0.1 mg (With BSA & Azide at 0.2mg/mL)

• Products_type
  Antibody
• Products_short_name
  [Eosinophil Peroxidase]
• Products_name_syn
  [Eosinophil peroxidase heavy chain; EPER; EPO; EPP; EPX; EPX PEN; PERE]
• Other_names
  [eosinophil peroxidase preproprotein; Eosinophil peroxidase; eosinophil peroxidase; eosinophil peroxidase]
• Products_gene_name
  [EPX]
• Other_gene_names
  [EPX; EPX; EPO; EPP; EPX-PEN; EPER; EPO; EPP; EPO]
• Clonality
  Monoclonal
• Clone
  [EPO104]
• Reactivity
  Human.
• Specificity
  Peripheral blood granulocytes are classified into neutrophils, basophils and eosinophils according to the staining characteristics of their cytoplasmic granules. Granule proteins are released by physiologic and pharmacologic stimuli and play important roles in both normal and pathological host immune responses. Eosinophil major basic protein and eosinophil peroxidase (EPX) are granule proteins specific to the eosinophil. AHE-1 recognizes human EPX, a granule protein specific to eosinophils. It does not cross-react with eosinophil major basic protein, elastase, cathepsin G, esterase N, thrombin, plasmin, kallikrein, lactoferrin, or transferrin. This MAb stains eosinophils only and does not stain other peripheral blood cells, including platelets, neutrophils, monocytes, lymphocytes or red blood cells. Human EPX gene product can form a tetramer of two light chains and two heavy chains. Other peroxidase family members include myeloperoxidase (MPO), lactoperoxidase (LPO), and thyroid peroxidase (TPO).
• Form
  200ug/ml of AB purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Storage_stability
  Store at 2 to 8 degree C. Antibody is stable for 24 months.
• Tested_application
  ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistology (IH)
• Conjugate
  Peroxidases with EC number 1.11.1.x are catalyzing the reaction of ROOR' + electron donor (2 e−) + 2H+ → ROH + R'OH

• Gene target
  Eosinophil  
• Gene symbol
  EGOT, EPX
• Short name
  Eosinophil
• Host
  Mouse
• Isotype
  IgG1, kappa
• Label
  peroxidase
• Alternative name
  Eosinophil Peroxidase

Gene info

• Identity
  HGNC:37129
• Gene
  EGOT
• Long gene name
  eosinophil granule ontogeny transcript
• Synonyms gene name
  • eosinophil granule ontogeny transcript (non-protein coding)
• Synonyms
  • EGO
  • NCRNA00190
• Synonyms name
  • eosinophil granule ontogeny
  • non-protein coding RNA 190
• GenBank acession
  • BC039547
• Locus
  3p26.1
• Discovery year
  2009-07-28
• Entrez gene record
  100126791
• Pubmed identfication
  • 17351112
  • 22303364
• RefSeq identity
  • NR_004428
• Classification
  • Long non-coding RNAs with non-systematic symbols
• VEGA ID
  OTTHUMG00000156235

Gene info

• Identity
  HGNC:3423
• Gene
  EPX
• Long gene name
  eosinophil peroxidase
• Synonyms
  • EPO
  • EPP
  • EPX-PEN
• GenBank acession
  • M26515
• Locus
  17q22
• Discovery year
  1998-11-24
• Entrez gene record
  8288
• Pubmed identfication
  • 2550461
  • 2541222
• RefSeq identity
  • NM_000502
• VEGA ID
  OTTHUMG00000178802

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