Recombinant Human Neutrophil elastase (ELANE)

• Catalog number
  RPC20226-100ug
• Price
  Please ask
• Size
  100ug

• Estimated Turnaround Time
  5-7 weeks
• Gene Name
  ELANE
• Alternative Names
  Bone marrow serine protease; Elastase-2Human leukocyte elastase; HLEMedullasin; PMN elastase
• Source
  Yeast
• Purity
  > 90% by SDS-PAGE
• Shipping Conditions
  Ice packs
• Storage conditions
  Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.
• Shelf life
  12 months in lyophilized form; 6 months in solution form.
• Restriction
  For research use only. Not for diagnostic procedures.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Neutrophil   elastase   ELANE  
• Gene symbol
  ELANE
• Short name
  Recombinant Neutrophil elastase (ELANE)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biomatik advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Homo sapiens (Human), Humans
• Alternative name
  Rec. H. sapiens Neutrophil elastase (elastase, neutrophil expressed)
• Alternative technique
  rec
• Alternative to gene target
  elastase, neutrophil expressed, ELA2 and GE and HLE and HNE and NE and PMN-E and SCN1, ELANE and IDBG-13111 and ENSG00000197561 and 1991, cytokine binding, Extracellular, Elane and IDBG-171367 and ENSMUSG00000020125 and 50701, ELA2 and IDBG-645525 and ENSBTAG00000046188 and 100126050

Gene info

• Identity
  HGNC:3309
• Gene
  ELANE
• Long gene name
  elastase, neutrophil expressed
• Synonyms gene
  • ELA2
• Synonyms gene name
  • elastase 2, neutrophil
• Synonyms
  • NE
  • HNE
  • HLE
  • PMN-E
• Synonyms name
  • neutrophil elastase
  • leukocyte elastase
  • medullasin
  • PMN Elastase
  • polymorphonuclear leukocyte elastase
• Locus
  19p13.3
• Discovery year
  1989-09-08
• Entrez gene record
  1991
• Pubmed identfication
  • 2902087
• RefSeq identity
  • NM_001972
• Classification
  • Granule associated serine proteases of immune defence
  • Complement system regulators and receptors
• VEGA ID
  OTTHUMG00000181839
• Locus Specific Databases
  • ELA2base: Mutation registry for Cyclic and congenital neutropenia
  • LRG_57

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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