Active Tumor Necrosis Factor Related Apoptosis Inducing Ligand (TRAIL)
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Catalog numberRPU54878-1mg
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Price:
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Size1mg
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Estimated Turnaround Time6-11 business days
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Gene NameNA
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Alternative NamesCD253; TNFSF10; APO2L; Apo2-L; TL2; TRAIL; Tumor Necrosis Factor Ligand Superfamily Member 10; Apo-2 Ligand
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SourceNA
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Purity> 95%
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ApplicationCell culture; Activity Assays.
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Shipping ConditionsIce packs
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Storage conditionsShort term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.
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Shelf life1 year
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RestrictionFor research use only. Not for diagnostic procedures.
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DescriptionThis 1 is suited for programmed cell-death studies. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
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Gene target
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Gene symbolTNFSF10, TNFRSF10B
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Short nameActive Tumor Necrosis Factor Apoptosis Ligand (TRAIL)
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Techniqueapoptosis, apoptosis pathway
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SpeciesHomo sapiens (Human)
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Alternative namefunctionnal Tumor Necrosis Factor Related programmed cellular destruction Inducing Ligand (TRAIL)
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Alternative techniquecelldeath
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Tissuetumor
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Gene info
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Identity
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Gene
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Long gene nameTNF superfamily member 10
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Synonyms gene name
- tumor necrosis factor (ligand) superfamily, member 10
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-12-04
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Pubmed identfication
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Classification
- CD molecules
- Tumor necrosis factor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 10b
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 10b
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-12-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tumor necrosis factor receptor superfamily
- CD molecules
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VEGA ID
MeSH Data
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Name
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ConceptScope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
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Tree numbers
- E01.370.225.500.383.910
- E01.370.225.500.388.930
- E05.200.500.383.910
- E05.200.500.388.930
- E05.242.383.910
- E05.242.417.500
- E05.337.550.200.800
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data