LSD1/AOF2 Antibody

• Catalog number
  BF0551
• Price
  Please ask
• Size
  50µL

• Type
  primary antibody
• Shipping
  Ice bag
• Antigen
  LSD1/AOF2
• Reactivity
  Human,Mouse,Monkey
• Clonality
  Monoclonal
• Application
  WB,IHC,ELISA
• Application_advice
  ELISA 1/10000, WB 1/500 - 1/2000, IHC 1/200 - 1/1000
• Immunogen
  Purified recombinant fragment of human LSD1/AOF2 expressed in E. Coli.
• Purification
  Affinity-chromatography.
• Format
  Liquid
• Concentration
  1mg/ml
• Fragment
  Fab fragment
• Storage_Buffer
  Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
• Specificity
  LSD1/AOF2 antibody detects endogenous levels of total LSD1/AOF2.
• GendID
  23028
• Gene
  KDM1A
• GeneAlias
  KDM1A AOF2 KDM1 KIAA0601 LSD1
• Unigene
  Hs.591518;
• Swiss Prot
  O60341
• Weight
  93kDa
• Datasheet
• Msds
• Properties
  If you buy Antibodies supplied by Affinity Biosciences they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Additional gene
  Lysine-specific demethylase 1 (LSD1), the first identified histone demethylase, was belonged to the superfamily of the Flavin adenine dinucleotide (FAD)-dependent amine oxidases. LSD1 specifically demethylates mono- or dimethylated dimethylated histone H3 lysine4 (H3K4) and H3 lysine 9 (H3K9) via a redox process. Recently evidences showed that LSD1 played an important role in a broad spectrum of biological processes, including cell proliferation, adipogenesis, spermatogenesis, chromosome segregation and embryonic development. Furthermore, LSD1 also could promote progress of tumor by inhibiting the tumor suppressor activity of p53. To date, as a potential drug for discovering anti-tumor drugs, the medical significance of LSD1 inhibitors have been greatly appreciated. Here, we reviewed the remarkable progress being made in understanding of LSD1, mainly on its structure, basic function and medical application in tumor therapy.
• French translation
  anticorps

• Gene target
  LSD1/AOF2  
• Gene symbol
  KDM1A
• Short name
  LSD1/AOF2 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Mouse
• Isotype
  IgG1
• Alternative name
  LSD1/AOF2 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:29079
• Gene
  KDM1A
• Long gene name
  lysine demethylase 1A
• Synonyms gene
  • AOF2
  • KDM1
• Synonyms gene name
  • amine oxidase (flavin containing) domain 2
  • lysine (K)-specific demethylase 1
• Synonyms
  • KIAA0601
  • BHC110
  • LSD1
• Synonyms name
  • Lysine-specific histone demethylase 1A
• GenBank acession
  • AL031428
• Locus
  1p36.12
• Discovery year
  2004-02-26
• Entrez gene record
  23028
• Pubmed identfication
  • 9628581
  • 12493763
• RefSeq identity
  • NM_015013
• Classification
  • MicroRNA protein coding host genes
  • Lysine demethylases
• VEGA ID
  OTTHUMG00000003220

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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