anti-Caspase-14 Antibody
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Catalog number2509
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoCaspase-14 Antibody: Caspases are a family of cysteine proteases that can be divided into apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1b and IL-18. Caspase-14 is highly expressed in embryonic but not adult tissues. It is processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in the keratinocyte terminal differentiation, which is important for the formation of the skin barrier.
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Gene namesCaspase-14 Antibody: MICE, mini-ICE, Caspase-14, Mini-ICE, CASP-14
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Antibodie s labelunlabelled serum
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PurityCaspase-14 Antibody is affinity chromatography purified via peptide column.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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AntigenCaspase-14 antibody was made against a 16 amino acid synthetic peptide from near the carboxy terminus of human caspase-14.
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Immuno applicationELISA, Western Blot, immuno-histo-chemistry
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Antibody adviceCaspase-14 antibody can be used for the detection of caspase-14 by Western blot at 1 ug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 ug/mL.
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Suspention pH azideCaspase-14 Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atCaspase-14 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman, Mouse, Rat
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Omim nr6753280
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Ncbi nrNP_033939
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Vial with antibodyin solution
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NCBI GENE nr12365
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GENE symbolCasp14
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Antigene namecaspase 14
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SourceMus musculus
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Protein nrO89094
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolCASP14, CARD14
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Short nameanti-Caspase-14 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toCasp-14 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namecaspase 14
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Synonyms gene name
- caspase 14, apoptosis-related cysteine protease
- caspase 14, apoptosis-related cysteine peptidase
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Synonyms
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Synonyms name
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Locus
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Discovery year1998-11-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecaspase recruitment domain family member 14
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Synonyms gene
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Synonyms gene name
- psoriasis susceptibility 2
- caspase recruitment domain family, member 14
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-09-19
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Entrez gene record
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Pubmed identfication
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Classification
- Membrane associated guanylate kinases
- PDZ domain containing
- Caspase recruitment domain containing
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
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Tree numbers
- E05.599.495
