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anti-Caspase-14 Antibody

anti-Caspase-14 Antibody is available 1 time from Proscience labs

2509 | anti-Caspase-14 Antibody size: 0.02 mg, 0.1 mg | 215.75 USD

Catalog number 2509
Supplier proscience
Price 215.75 USD
Size 0.02 mg, 0.1 mg
1. Gene info
Identity 1502
Gene CASP14
Long gene name caspase 14
Synonyms gene name
  • caspase 14, apoptosis-related cysteine protease
  • caspase 14, apoptosis-related cysteine peptidase
Synonyms
  • MICE
  • MGC119078
  • MGC119079
Synonyms name
  • apoptosis-related cysteine protease
Locus 19p13.12
Discovery year 1998-11-09
Entrez gene record 23581
Pubmed identfication
  • 10203698
  • 9792675
  • 15301553
RefSeq identity
  • NM_012114
Classification
  • Caspases
Havana BLAST/BLAT OTTHUMG00000183205
Gene info Caspase-14 Antibody: Caspases are a family of cysteine proteases that can be divided into apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1b and IL-18. Caspase-14 is highly expressed in embryonic but not adult tissues. It is processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in the keratinocyte terminal differentiation, which is important for the formation of the skin barrier.
Gene names Caspase-14 Antibody: MICE, mini-ICE, Caspase-14, Mini-ICE, CASP-14
Antibodie's label unlabelled serum
Purity Caspase-14 Antibody is affinity chromatography purified via peptide column.
Ab raised in Rabbit
Type Polyclonal
Immunoglobulin IgG
Antigen Caspase-14 antibody was made against a 16 amino acid synthetic peptide from near the carboxy terminus of human caspase-14.
Immuno application ELISA, Western Blot, immuno-histo-chemistry
Antibody advice Caspase-14 antibody can be used for the detection of caspase-14 by Western blot at 1 ug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 ug/mL.
Suspention, pH, azide Caspase-14 Antibody is supplied in PBS containing 0.02% sodium azide.
Keep at Caspase-14 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Works with Human, Mouse, Rat
Omim nr 6753280
Ncbi nr NP_033939
Vial with antibody in solution
NCBI GENE nr 12365
GENE symbol Casp14
Antigene name caspase 14
Source Mus musculus
Protein nr O89094
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
Properties If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation anticorps
Gene targetCaspase-14
Short name anti-Caspase-14 Antibody
Technique Antibody, anti
Alternative name antibody to-caspase-14 (Antibody to)
Alternative technique antibodies
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