Iron Chelator, Dp44MT

• Catalog number
  9634-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  2-(Di-2-pyridinylmethylene)-N,N-dimethyl-hydrazinecarbothioamide, Di-2-pyridylketone-4,4,-dimethyl-3-thiosemicarbazone
• Description
  Dp44MT is a cell-permeable iron chelator. This di-2-pyridyl thiosemicarbazone (DpT) based tridentate ligand displays potent and selective antiproliferative properties in neoplastic cells and minimally affects normal cells. Dp44mT prevents aggressive growth of M109 lung carcinoma in mice and has been shown to mobilize cellular iron effectively, and generate ROS leading to apoptosis.
• CAS Number
  152095-12-0
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₄H₁₅N₅S
• Molecular Weight
  285.37
• Cell Permeable
  Yes
• Purity
  ≥98%
• Solubilities
  DMSO (>5 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A cell-permeable iron chelator
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD20527329
• PubChem CID
  10334137
• PubChem CID Link
• SMILES
  CN(C)C(=S)NN=C(C1=CC=CC=N1)C2=CC=CC=N2
• InChi
  InChI=1S/C14H15N5S/c1-19(2)14(20)18-17-13(11-7-3-5-9-15-11)12-8-4-6-10-16-12/h3-10H,1-2H3,(H,18,20)
• InChi Key
  XOBIGRNRXCAMJQ-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Iron   Chelator   Dp44MT  
• Short name
  Iron Chelator, Dp44MT
• Alternative name
  Iron Chelator, Dp44MT

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