Hinokitiol, Iron Chelator antioxidant
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Catalog number
SIH-151-250MG
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Price
Please ask
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Size
250 mg
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Stock availabilitIn Stock
In Stock
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CAS number
499-44-5
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Description
Iron Chelator antioxidant
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Molecular weight
165,2 g/mol
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Primary research fields
Cancer, Oxidative Stress
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Other name
2-Hydroxy-4-isopropyl-2,4,6-cycloheptatrien-1-one
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Product category
Small Molecules
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Product type
Antioxidant
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Chemical formula
C10H12O3
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Origin
Synthetic
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Purity pourcentage
>98%
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Soluble in
Soluble in DMSO or ethanol (25 mg/ml)
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Physical appearance
White Solid
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Storage recommendations
-20ÂșC
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Shipping recommendations
Shipped Ambient
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Safety information
Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Hazard Phrases: H302
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PubChem number
3611
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Scientific context
Hinokitiol is a natural monoterpenoid. It is a potent metal chelator that induces differentiation and apoptosis in teratocarcinoma F9 cells (1), mediated by activation of caspase-3 (2). It also inhibits tyrosinase most likely via metal chelation (3).
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Bibliography
1. Tanaka T., et al. (1999) Cell Biol Int. 23(8): 541-550. 2. Ido Y., et al. (1999) Cell Prolif. 32(1): 63-73 3. Kim D.S., et al. (2004) Arch Pharm Res. 27(3): 334-339.
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Release date
16-May-2011
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PubMed number
Refer to PubMed
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Tested applications
To be tested
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Tested reactivity
To be tested
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Representative figure legend
Chemical structure of Hinokitiol (SIH-151), a Iron Chelator antioxidant. CAS #: 499-44-6. Molecular Formula: C10H12O3. Molecular Weight: 165.2 g/mol. Chemical structure of Hinokitiol, a Iron Chelator antioxidant (SIH-151). CAS # 499-44-6. Molecular Formula: C10H12O3.
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Warning information
Non-hazardous
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Country of production
Canada
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Total weight kg
0.25
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Net weight g
0.25
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Gene target
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Short name
Hinokitiol, Iron Chelator antioxidant
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Alternative name
Hinokitiol, Iron Chelator antioxidant
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MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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