TREM1, human recombinant

• Catalog number
  7332-100
• Price
  Please ask
• Size
  100 ug

• Synonyms
  Triggering receptor expressed on myeloid cells 1, CD354, TREM-1
• Alternative_names
  Triggering receptor expressed on myeloid cells 1, CD354, TREM-1
• Description
  Amplifies neutrophil and monocyte-mediated inflammatory responses
• Recombinant
  Yes
• Source
  E. coli
• Purity by SDS PAGE
  ≥85%
• Assay
  SDS-PAGE
• Endotoxin Level
  < 1.0 EU per 1 microgram of protein
• Molecular Weight
  23.3 kDa (209 aa, 21-205 aa + His Tag), confirmed by MALDI-TOF.
• Storage Temp
  -80°C
• Shipping
  Dry Ice
• Shelf Life
  12 months
• Concentration
  0.5 mg/ml
• Appearance
  Liquid
• Physical form description
  0.5 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 30% glycerol and 1 mM DTT.
• Background Information
  TREM1 is a receptor belonging to the Ig super family that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. Recombinant human TREM1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Amino acid sequence
  MGSSHHHHHH SSGLVPRGSH MGSM ATKLTE EKYELKEGQT LDVKCDYTLE KFASSQKAWQ IIRDGEMPKT LACTERPSKN SHPVQVGRII LEDYHDHGLL RVRMVNLQVE DSGLYQCVIY QPPKEPHMLF DRIRLVVTKG FSGTPGSNEN STQNVYKIPP TTTKALCPLY TSPRTVTQAP PKSTADVSTP DSEINLTNVT DIIRVPVFN
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  TREM1  
• Gene symbol
  TREM1
• Short name
  TREM1, recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  triggering receptor expressed on myeloid cells 1, H. sapiens Rec.
• Alternative technique
  rec
• Alternative to gene target
  triggering receptor expressed on myeloid cells 1, TREM1 and IDBG-86629 and ENSG00000124731 and 54210, scaffold protein binding, Extracellular, Trem1 and IDBG-189794 and ENSMUSG00000042265 and 58217, TREM1 and IDBG-630874 and ENSBTAG00000017593 and 404547

Gene info

• Identity
  HGNC:17760
• Gene
  TREM1
• Long gene name
  triggering receptor expressed on myeloid cells 1
• Synonyms
  • TREM-1
  • CD354
• GenBank acession
  • AF196329
• Locus
  6p21.1
• Discovery year
  2002-08-09
• Entrez gene record
  54210
• Pubmed identfication
  • 11922939
  • 10799849
• RefSeq identity
  • NM_018643
• Classification
  • V-set domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000014674

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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