NFKB1 (Ser903) Antibody, ALEXA FLUOR 555

• Catalog number
  bs-5509R-A555
• Price
  Please ask
• Size
  100ul

• Long name
  NFKB1 (Ser903) Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
• Also known as
  Anti-NFKB1 Ser903 PAb ALEXA FLUOR 555
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 555
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  NFKB1 Ser903
• Specificity
  This is a highly specific antibody against NFKB1 Ser903.
• Modification
  Phosphorylation
• Modification Site
  Ser903
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from human NF KappaB p105 around the phosphorylation site of Ser903 [AH(p-S)LP]
• Gene ID Number
  4790
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. SUBUNIT: Active NF-kappa-B is a heterodimer of an about 50 kDa DNA-binding subunit and the weak DNA-binding subunit p65. Two heterodimers might form a labile tetramer. Also interacts with MAP3K8. NF-kappa-B p50 subunit interacts with NCOA3 coactivator, which may coactivate NF-kappa-B dependent expression via its histone acetyltransferase activity. Interacts with DSIPI; this interaction prevents nuclear translocation and DNA-binding. Interacts with SPAG9 and UNC5CL.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  553nm/568nm
• Synonyms
  DKFZp686C01211; DNA binding factor KBF1; DNA binding factor KBF1 EBP1; DNA binding factor KBF1 EBP1; DNA-binding factor KBF1; EBP 1; EBP-1; EBP1; KBF1; MGC54151; NF kappa B; NF kappabeta; NF kB1; NFKB 1; NFKB p105; NFKB p50; NFKB1; NFKB1_HUMAN; Nuclear factor kappa B DNA binding subunit; Nuclear factor NF kappa B p105 subunit; Nuclear factor NF kappa B p50 subunit; Nuclear factor NF-kappa-B p50 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B cells 1; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; p84/NF-kappa-B1 p98.
• Properties
  For facs or microscopy Alexa 1 conjugate. Very high photo stable ALEXA conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 555
• French translation
  anticorps

• Gene target
  NFKB1   Ser903  
• Gene symbol
  NFKB1
• Short name
  Anti-NFKB1 Ser903
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 555
• Alternative name
  NFKB1 (Ser903) Polyclonal Antibody, ALEXA FLUOR 555
• Alternative technique
  antibodies
• Alternative to gene target
  nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, EBP-1 and KBF1 and NF-kappa-B and NF-kappaB and NF-kB1 and NFkappaB and NFKB-p105 and NFKB-p50 and p105 and p50, NFKB1 and IDBG-31974 and ENSG00000109320 and 4790, transcription regulatory region DNA binding, nuclei, Nfkb1 and IDBG-195445 and ENSMUSG00000028163 and 18033, BT.60919 and IDBG-640840 and ENSBTAG00000020270 and 616115

Gene info

• Identity
  HGNC:7794
• Gene
  NFKB1
• Long gene name
  nuclear factor kappa B subunit 1
• Synonyms gene name
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
• Synonyms
  • KBF1
  • p105
  • NFKB-p50
  • p50
  • NF-kappaB
  • NFkappaB
  • NF-kB1
• Synonyms name
  • Nuclear factor NF-kappa-B p105 subunit
• GenBank acession
  • M58603
• Locus
  4q24
• Discovery year
  1991-11-14
• Entrez gene record
  4790
• Pubmed identfication
  • 1992489
• RefSeq identity
  • NM_003998
• Classification
  • NF-kappa B complex subunits
  • Ankyrin repeat domain containing
  • IPT domain containing
• VEGA ID
  OTTHUMG00000161080
• Locus Specific Databases
  • LRG_1316

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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