- Catalog numberbs-5512R-A555
- Product nameNFKB1 (Ser337) Antibody, ALEXA FLUOR 555
- Size100ul
- PriceAsk For Price
- Short nameAnti-NFKB1 Ser337
- Long nameNFKB1 (Ser337) Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
- Also known asAnti-NFKB1 Ser337 PAb ALEXA FLUOR 555
- CategoryConjugated Primary Antibodies
- Conjugated withALEXA FLUOR® 555
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenNFKB1 Ser337
- SpecificityThis is a highly specific antibody against NFKB1 Ser337.
- ModificationPhosphorylation
- Modification SiteSer337
- ClonalityPolyclonal
- ClonePolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- SourceKLH conjugated synthetic phosphopeptide derived from human NF KappaB p105 around the phosphorylation site of Ser337
- Gene ID Number4790
- Tested applicationsIF(IHC-P)
- Recommended dilutionsIF(IHC-P)(1:50-200)
- CrossreactivityHuman
- Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Background of the antigenThis gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].
- PurificationPurified by Protein A.
- Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
- Excitation emission553nm/568nm
- SynonymsDKFZp686C01211; DNA binding factor KBF1; DNA binding factor KBF1 EBP1; DNA binding factor KBF1 EBP1; DNA-binding factor KBF1; EBP 1; EBP-1; EBP1; KBF1; MGC54151; NF kappa B; NF kappabeta; NF kB1; NFKB 1; NFKB p105; NFKB p50; NFKB1; NFKB1_HUMAN; Nuclear factor kappa B DNA binding subunit; Nuclear factor NF kappa B p105 subunit; Nuclear factor NF kappa B p50 subunit; Nuclear factor NF-kappa-B p50 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B cells 1; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; p84/NF-kappa-B1 p98.
- Alternative to gene target
- [ "nuclear factor of kappa light polypeptide gene enhancer in B-cells 1", "EBP-1 and KBF1 and NF-kappa-B and NF-kappaB and NF-kB1 and NFkappaB and NFKB-p105 and NFKB-p50 and p105 and p50", "NFKB1 and IDBG-31974 and ENSG00000109320 and 4790", "transcription regulatory region DNA binding", "nuclei", "Nfkb1 and IDBG-195445 and ENSMUSG00000028163 and 18033", "BT.60919 and IDBG-640840 and ENSBTAG00000020270 and 616115" ]
- Gene targetNFKB1 Ser337
- Identity:HGNC:7794
- Gene:NFKB1
- Long gene name:nuclear factor kappa B subunit 1
- Synonyms gene name:nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
- Synonyms:KBF1p105NFKB-p50p50NF-kappaBNFkappaBNF-kB1
- Discovery year:1991-11-14
- Entrez gene record:4790
- Pubmed identification:1992489
- RefSeq identity:NM_003998
- Classification:NF-kappa B complex subunits, Ankyrin repeat domain containing, IPT domain containing
- VEGA ID:OTTHUMG00000161080
- Gene symbolNFKB1
- isotype filter
- Immunoglobulin G IgG
- LabelALEXA FLUOR 555
- label filter
- ALEXA FLUOR 555
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies
Gene info
Locus Specific Databases:LRG_1316