KC7F2

• Catalog number
  9641-50
• Price
  Please ask
• Size
  50 mg

• Alternative_name
  N,N'-(dithiodi-2,1-ethanediyl)bis[2,5-dichloro-benzenesulfonamide
• Description
  KC7F2 is a small molecule HIF-1 pathway inhibitor that inhibits HIF-1α protein translation, but not transcription. It inhibits hypoxia-induced expression of several HIF target genes, such as carbonic anhydrase IX, matrix metalloproteinase 2, enolase 1, and endothelin 1. KC7F2 is cytotoxic to a variety of cancer cell lines with an IC₅₀ value of 15-25 µM.
• CAS Number
  927822-86-4
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₆H₁₆Cl₄N₂O₄S₄
• Molecular Weight
  570.38
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>50 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A small molecule HIF-1 pathway inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  16047442
• PubChem CID Link
• SMILES
  C1=CC(=C(C=C1Cl)S(=O)(=O)NCCSSCCNS(=O)(=O)C2=C(C=CC(=C2)Cl)Cl)Cl
• InChi
  InChI=1S/C16H16Cl4N2O4S4/c17-11-1-3-13(19)15(9-11)29(23,24)21-5-7-27-28-8-6-22-30(25,26)16-10-12(18)2-4-14(16)20/h1-4,9-10,21-22H,5-8H2
• InChi Key
  REQLACDIZMLXIC-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  KC7F2  
• Short name
  KC7F2
• Alternative name
  KC7F2

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