Akt-I-1

• Catalog number
  B1610-1
• Price
  Please ask
• Size
  1 mg

• Alternative_name
  Akt-I-1; AktI1; Akt-I1; AKT-I-1; N3-(7-Cyclobutyl-3-phenyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)-N1,N1,2,2-tetramethyl-1,3-propanediamine
• Description
  Akt-I-1 is a specific inhibitor of Akt1 (IC(50) 4.6 µM) and does not inhibit AKT2, or AKT3
• CAS Number
  473382-39-7
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₂H₃₀N₆
• Molecular Weight
  378.5
• Cell Permeable
  Yes
• Purity
  ≥98%
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A specific inhibitor of Akt1
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD16038643
• PubChem CID
  10271028
• PubChem CID Link
• SMILES
  CC(C)(CNC1=NN2C(=NN=C2C3=CC=CC=C3)C=C1C4CCC4)CN(C)C
• InChi
  1S/C22H30N6/c1-22(2,15-27(3)4)14-23-20-18(16-11-8-12-16)13-19-24-25-21(28(19)26-20)17-9-6-5-7-10-17/h5-7,9-10,13,16H,8,11-12,14-15H2,1-4H3,(H,23,26)
• InChi Key
  FKCXKEHHZXEWGP-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Akt-I-1  
• Gene symbol
  SNORD113-1, NISCH, FABP6, NT5C, DDX58, SEMA3A, TANK, FABP2, PSMB2, CPLX1
• Short name
  Akt-I-1
• Alternative name
  Akt-I-1

Gene info

• Identity
  HGNC:32980
• Gene
  SNORD113-1
• Long gene name
  small nucleolar RNA, C/D box 113-1
• Synonyms
  • 14q(I-1)
• Locus
  14q32.31
• Discovery year
  2006-09-20
• Entrez gene record
  767561
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003229.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:18006
• Gene
  NISCH
• Long gene name
  nischarin
• Synonyms
  • KIAA0975
  • I-1
  • IRAS
• Synonyms name
  • imidazoline receptor candidate
  • I-1 receptor candidate protein
  • imidazoline receptor antisera selected
• GenBank acession
  • AF082516
• Locus
  3p21.1
• Discovery year
  2002-01-16
• Entrez gene record
  11188
• Pubmed identfication
  • 11912194
  • 10882231
• RefSeq identity
  • NM_007184
• VEGA ID
  OTTHUMG00000158571

Gene info

• Identity
  HGNC:3561
• Gene
  FABP6
• Long gene name
  fatty acid binding protein 6
• Synonyms gene name
  • fatty acid binding protein 6, ileal
• Synonyms
  • I-15P
  • ILLBP
  • I-BAP
  • ILBP3
  • I-BABP
  • ILBP
  • I-BALB
• Synonyms name
  • illeal lipid-binding protein
  • ileal bile acid binding protein
  • gastrotropin
• GenBank acession
  • U19869
• Locus
  5q33.3
• Discovery year
  1997-09-12
• Entrez gene record
  2172
• Pubmed identfication
  • 7894165
  • 7619861
• RefSeq identity
  • NM_001040442
• Classification
  • Fatty acid binding protein family
• VEGA ID
  OTTHUMG00000130329

Gene info

• Identity
  HGNC:17144
• Gene
  NT5C
• Long gene name
  5', 3'-nucleotidase, cytosolic
• Synonyms gene
  • UMPH2
• Synonyms gene name
  • 5' nucleotidase, deoxy (pyrimidine), cytosolic type C
  • uridine 5-prime monophosphate hydrolase 2
• Synonyms
  • DNT1
  • DNT-1
  • PN-I
  • cdN
  • dNT-1
• GenBank acession
  • AF154829
• Locus
  17q25
• Discovery year
  2001-11-20
• Entrez gene record
  30833
• Pubmed identfication
  • 10899995
• Classification
  • 5'-nucleotidases
• VEGA ID
  OTTHUMG00000179346

Gene info

• Identity
  HGNC:19102
• Gene
  DDX58
• Long gene name
  DExD/H-box helicase 58
• Synonyms gene name
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
• Synonyms
  • RIG-I
  • FLJ13599
  • DKFZp434J1111
  • RIG-1
  • RIG1
• Synonyms name
  • RNA helicase RIG-I
  • retinoic acid inducible gene I
• GenBank acession
  • AF038963
• Locus
  9p21.1
• Discovery year
  2004-05-10
• Entrez gene record
  23586
• Pubmed identfication
  • 21690088
• RefSeq identity
  • NM_014314
• Classification
  • DEAD-box helicases
  • Caspase recruitment domain containing
• VEGA ID
  OTTHUMG00000019746

Gene info

• Identity
  HGNC:10723
• Gene
  SEMA3A
• Long gene name
  semaphorin 3A
• Synonyms gene
  • SEMAD
• Synonyms gene name
  • sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
• Synonyms
  • SEMA1
  • SemD
  • coll-1
  • Hsema-I
• Synonyms name
  • sema III
• GenBank acession
  • L26081
• Locus
  7q21.11
• Discovery year
  1999-06-25
• Entrez gene record
  10371
• Pubmed identfication
  • 8269517
  • 7748561
• RefSeq identity
  • NM_006080
• Classification
  • Immunoglobulin like domain containing
  • Semaphorins
• VEGA ID
  OTTHUMG00000023443

Gene info

• Identity
  HGNC:11562
• Gene
  TANK
• Long gene name
  TRAF family member associated NFKB activator
• Synonyms gene
  • TRAF2
• Synonyms gene name
  • TRAF family member-associated NFKB activator
• Synonyms
  • I-TRAF
• GenBank acession
  • U59863
• Locus
  2q24.2
• Discovery year
  1997-06-12
• Entrez gene record
  10010
• Pubmed identfication
  • 8710854
  • 8855313
• RefSeq identity
  • NM_133484
• VEGA ID
  OTTHUMG00000132037

Gene info

• Identity
  HGNC:3556
• Gene
  FABP2
• Long gene name
  fatty acid binding protein 2
• Synonyms gene name
  • fatty acid binding protein 2, intestinal
• Synonyms
  • I-FABP
• GenBank acession
  • J03465
• Locus
  4q26
• Discovery year
  1986-01-01
• Entrez gene record
  2169
• RefSeq identity
  • NM_000134
• Classification
  • Fatty acid binding protein family
• VEGA ID
  OTTHUMG00000132972

Gene info

• Identity
  HGNC:9539
• Gene
  PSMB2
• Long gene name
  proteasome 20S subunit beta 2
• Synonyms gene name
  • proteasome (prosome, macropain) subunit, beta type, 2
  • proteasome subunit beta 2
• Synonyms
  • HC7-I
• Synonyms name
  • proteasome subunit β4
• GenBank acession
  • D26599
• Locus
  1p34.3
• Discovery year
  1995-05-03
• Entrez gene record
  5690
• Pubmed identfication
  • 7918633
• RefSeq identity
  • NM_002794
• Classification
  • Proteasome
• VEGA ID
  OTTHUMG00000004169

Gene info

• Identity
  HGNC:2309
• Gene
  CPLX1
• Long gene name
  complexin 1
• Synonyms
  • CPX-I
• GenBank acession
  • AF022383
• Locus
  4p16.3
• Discovery year
  1999-09-09
• Entrez gene record
  10815
• Pubmed identfication
  • 7553862
• VEGA ID
  OTTHUMG00000160005

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