CD154, soluble (CD40 Ligand, CD40-L, CD40L, CD40LG, gp39, hCD40L, HIGM1, IGM, IMD3, T-BAM, T-cell Antigen GP39, TNF-related Activation Protein, TRAP, Tumor Necrosis Factor Ligand Superfamily Member 5, TNF Ligand Superfamily Member 5, TNFSF5)[CD154, soluble]

• Catalog number
  MBS609808
• Price
  Please ask
• Size
  NA

• Products_type
  Antibody
• Reactivity
  Human
• Description
  Antigens are peptides or recombinant or native dependent on the production method. For cells, cell lines and tissues in culture till half confluency. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
• Properties
  Immunoglobulin M, or IgM for short, is a basic antibody that is produced by B cells. IgM is by far the physically largest antibody in the human circulatory system. It is the first antibody to appear in response to initial exposure to an antigen
• Gene
  Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.

• Gene target
  CD154   soluble   CD40   Ligand   CD40-L   CD40L   CD40LG   gp39   hCD40L   HIGM1   IMD3   T-BAM   GP39   TNF-related   Activation   Protein   TRAP   Tumor   Necrosis   Factor   Ligand   Superfamily   Member   TNF   Ligand   Superfamily   Member   TNFSF5   [CD154   soluble]  
• Gene symbol
  CD40LG, TNF, TNFRSF1A, TNFRSF1B, CD40, LTBR, TBXT, ACP5, PLS3, CHI3L1
• Short name
  CD154, soluble (CD40 Ligand, CD40-L, CD40L, CD40LG, gp39, hCD40L, HIGM1, IGM, IMD3, T-BAM, T- Antigen GP39, TNF- Activation Protein, TRAP, Tumor Necrosis Factor Ligand Superfamily Member 5, TNF Ligand Superfamily Member 5, TNFSF5)[CD154, soluble]
• Technique
  activation, antigen, IgM, antigenes, IgMs
• Host
  Mouse
• Isotype
  IgM, IgM
• Alternative name
  CD154, soluble (CD40 molecule, tumor necrosis factor receptor superfamily member 5 Ligand, CD40 molecule, tumor necrosis factor receptor superfamily member 5-L, CD40L, CD40 molecule, tumor necrosis factor receptor superfamily member 5 ligand, gp39, hCD40L, HIGM1, Immunoglobulin M, IMD3, T-BAM, T-cellular protein GP39, tumor necrosis factor-related Activation Protein, TRAP, Tumor Necrosis Factor Ligand supergroup Member 5, tumor necrosis factor Ligand supergroup Member 5, TNFSF5)[CD154, soluble]
• Alternative technique
  antigenes, immunoglobulin-m
• Alternative to gene target
  CD40 molecule, TNF receptor superfamily member 5, Bp50 and CDW40 and p50 and TNFRSF5, CD40 and IDBG-78904 and ENSG00000101017 and 958, ubiquitin protein ligase binding, Extracellular, Cd40 and IDBG-212533 and ENSMUSG00000017652 and 21939, BT.42498 and IDBG-643036 and ENSBTAG00000020736 and 286849
• Tissue
  cell, tumor

Gene info

• Identity
  HGNC:11935
• Gene
  CD40LG
• Long gene name
  CD40 ligand
• Synonyms gene
  • HIGM1
  • IMD3
  • TNFSF5
• Synonyms gene name
  • tumor necrosis factor (ligand) superfamily, member 5 (hyper-IgM syndrome)
• Synonyms
  • CD40L
  • TRAP
  • gp39
  • hCD40L
  • CD154
• Synonyms name
  • CD40 antigen ligand
  • tumor necrosis factor (ligand) superfamily member 5
  • T-B cell-activating molecule
  • TNF-related activation protein
  • hyper-IgM syndrome
• GenBank acession
  • X67878
• Locus
  Xq26.3
• Discovery year
  1989-06-30
• Entrez gene record
  959
• Pubmed identfication
  • 1427881
  • 7678782
• RefSeq identity
  • NM_000074
• Classification
  • CD molecules
  • Tumor necrosis factor superfamily
• VEGA ID
  OTTHUMG00000022512
• Locus Specific Databases
  • CD40Lbase: Mutation registry for X-linked Hyper-IgM syndrome
  • Global Variome shared LOVD
  • LRG_141

Gene info

• Identity
  HGNC:11892
• Gene
  TNF
• Long gene name
  tumor necrosis factor
• Synonyms gene
  • TNFA
• Synonyms gene name
  • tumor necrosis factor (TNF superfamily, member 2)
• Synonyms
  • TNFSF2
  • DIF
  • TNF-alpha
• Synonyms name
  • TNF superfamily, member 2
• GenBank acession
  • X02910
• Locus
  6p21.33
• Discovery year
  1986-01-01
• Entrez gene record
  7124
• Pubmed identfication
  • 2413547
  • 6392892
• Classification
  • Tumor necrosis factor superfamily
• VEGA ID
  OTTHUMG00000031194

Gene info

• Identity
  HGNC:11916
• Gene
  TNFRSF1A
• Long gene name
  TNF receptor superfamily member 1A
• Synonyms gene
  • TNFR1
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 1A
• Synonyms
  • TNF-R
  • TNFAR
  • TNFR60
  • TNF-R-I
  • CD120a
  • TNF-R55
• GenBank acession
  • M75866
• Locus
  12p13.31
• Discovery year
  1991-01-15
• Entrez gene record
  7132
• Pubmed identfication
  • 1655358
  • 2158863
• RefSeq identity
  • NM_001065
• Classification
  • Tumor necrosis factor receptor superfamily
  • CD molecules
• VEGA ID
  OTTHUMG00000168267
• Locus Specific Databases
  • INFEVERS: The repertory of Familial Mediterranean Fever (FMF) and Hereditary Inflammatory Disorders Mutations
  • LRG_193

Gene info

• Identity
  HGNC:11917
• Gene
  TNFRSF1B
• Long gene name
  TNF receptor superfamily member 1B
• Synonyms gene
  • TNFR2
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 1B
• Synonyms
  • TNFBR
  • TNFR80
  • TNF-R75
  • TNF-R-II
  • p75
  • CD120b
• GenBank acession
  • M32315
• Locus
  1p36.22
• Discovery year
  1991-01-15
• Entrez gene record
  7133
• Pubmed identfication
  • 2158863
  • 8702885
• RefSeq identity
  • NM_001066
• Classification
  • CD molecules
  • MicroRNA protein coding host genes
  • Tumor necrosis factor receptor superfamily
• VEGA ID
  OTTHUMG00000001829

Gene info

• Identity
  HGNC:11919
• Gene
  CD40
• Long gene name
  CD40 molecule
• Synonyms gene
  • TNFRSF5
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 5
  • CD40 molecule, TNF receptor superfamily member 5
• Synonyms
  • p50
  • Bp50
• GenBank acession
  • X60592
• Locus
  20q13.12
• Discovery year
  1993-08-27
• Entrez gene record
  958
• Pubmed identfication
  • 7687385
  • 2998589
• RefSeq identity
  • NM_001250
• Classification
  • CD molecules
  • Tumor necrosis factor receptor superfamily
• VEGA ID
  OTTHUMG00000033053
• Locus Specific Databases
  • CD40base: Mutation registry for CD40 deficiency (previously known as TNFRSF5base)
  • LRG_40

Gene info

• Identity
  HGNC:6718
• Gene
  LTBR
• Long gene name
  lymphotoxin beta receptor
• Synonyms gene
  • D12S370
• Synonyms
  • TNFCR
  • TNFR-RP
  • TNFR2-RP
  • TNF-R-III
  • TNFRSF3
• Synonyms name
  • TNFR superfamily, member 3
• GenBank acession
  • L04270
• Locus
  12p13.31
• Discovery year
  1996-03-12
• Entrez gene record
  4055
• Pubmed identfication
  • 8171323
  • 8486360
• Classification
  • Tumor necrosis factor receptor superfamily
• VEGA ID
  OTTHUMG00000168356

Gene info

• Identity
  HGNC:11515
• Gene
  TBXT
• Long gene name
  T-box transcription factor T
• Synonyms gene
  • T
• Synonyms gene name
  • T, brachyury homolog (mouse)
  • T brachyury transcription factor
• GenBank acession
  • AJ001699
• Locus
  6q27
• Discovery year
  1996-04-12
• Entrez gene record
  6862
• Pubmed identfication
  • 8963900
• RefSeq identity
  • NM_003181
• Classification
  • T-box transcription factors
• VEGA ID
  OTTHUMG00000015991

Gene info

• Identity
  HGNC:124
• Gene
  ACP5
• Long gene name
  acid phosphatase 5, tartrate resistant
• Synonyms
  • TRAP
  • HPAP
• Synonyms name
  • tartrate-resistant acid phosphatase
  • human purple acid phosphatase
• GenBank acession
  • X14618
• Locus
  19p13.2
• Discovery year
  1989-02-23
• Entrez gene record
  54
• Pubmed identfication
  • 8449511
  • 2338077
• Classification
  • Acid phosphatases
• VEGA ID
  OTTHUMG00000182036
• Locus Specific Databases
  • LRG_1218

Gene info

• Identity
  HGNC:9091
• Gene
  PLS3
• Long gene name
  plastin 3
• Synonyms gene name
  • plastin 3 (T isoform)
• Synonyms
  • T-plastin
• GenBank acession
  • L05491
• Locus
  Xq23
• Discovery year
  1997-08-18
• Entrez gene record
  5358
• Pubmed identfication
  • 8428952
• Classification
  • EF-hand domain containing
• VEGA ID
  OTTHUMG00000022237
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:1932
• Gene
  CHI3L1
• Long gene name
  chitinase 3 like 1
• Synonyms gene name
  • chitinase 3-like 1 (cartilage glycoprotein-39)
• Synonyms
  • GP39
  • YKL40
  • YK-40
• Synonyms name
  • cartilage glycoprotein-39
• GenBank acession
  • BC008568
• Locus
  1q32.1
• Discovery year
  1994-12-20
• Entrez gene record
  1116
• Pubmed identfication
  • 8245017
  • 9244440
• RefSeq identity
  • NM_001276
• Classification
  • Chitinases
• VEGA ID
  OTTHUMG00000042122

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