Mouse Anti-Desmin
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Catalog numberGEN570320
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PricePlease ask
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Size100ug
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Also known asDesmin
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Other namesdesmin; Desmin; desmin; mutant desmin p.K241E; intermediate filament protein; desmin; N/A
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CategoryAntibodies
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SubcategoryMnoclonal antibodies
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Gene nameDES; DES; CSM1; CSM2; LGMD2R; N/A
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Gene name synonimsDES; DES; CSM1; CSM2; LGMD2R; N/A
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Other gene namesDES; DES; CSM1; CSM2; LGMD2R; N/A
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ClonalityMonoclonal
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Immunoglobulin isotypeIgG1
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CloneD33
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Host organismMouse (Mus musculus)
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Species reactivityHuman (Homo sapiens), Hamster, Rat (Rattus norvegicus), Chicken; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivityThe antibody D33 reacts exclusively with desmin, which is expressed in smooth and striated muscle cells and their tumors e.g. rhabdomyosarcoma and leiomyosarcoma in human, hamster, rat and chicken. The antibody does not cross react with vimentin or any of the other intermediate filament proteins.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification methodN/A
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Form AppearanceEach vial contains 100ul 1mg/ml purified monoclonal antibody in phosphate buffered saline (PBS) containing 0.09% sodium azide
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ConcentrationN/A
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Storage and shippingStore the antibody at +4 degrees Celsius., or in small aliquots the antibody should be stored at -20 degrees Celsius..
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Tested applicationsImmunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, Western Blot (WB)
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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GeneDesmins or DES proteins detect by anti-desmin antibodies and DES ELISA kits. DSM1 and DSM2 play an important role in Desminopathy. Desmin regulated Myofibrilate Myopathy is a protein filament mutation of muscle proteins.
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TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus
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Gene target
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Gene symbolDES
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Short nameMouse Anti-Desmin
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Techniqueanti-, Mouse, anti, antibody to, antibodies, mouses
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Hostmouse
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SpeciesMouse, Mouses
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Alternative nameAnti-Mouse anti Desmin
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Alternative techniquemurine, antibodies
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Gene info
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Identity
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Gene
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Long gene namedesmin
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Intermediate filaments Type III
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data