Cleaved Caspase-1 (Arg317) /P10 Antibody

Type

primary antibody
Shipping

Ice bag
Antigen

Cleaved Caspase-1 (Arg317) /P10
Reactivity

Human,Mouse,Rat
Clonality

Polyclonal
Application

WB,IHC,IF/ICC
Application_advice

WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
Conjugate

Unconjugated
Epitope

Cleaved Arg317
Immunogen

The antiserum was produced against synthesized peptide derived from human Caspase 1.
Purification

The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Format

Liquid
Concentration

1mg/ml
Fragment

Fab fragment
Storage_Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Specificity

Caspase 1 (p10,Cleaved-Arg317) Antibody detects endogenous levels of fragment of activated Caspase 1 resulting from cleavage adjacent to Arg317.
GendID

834
Gene

CASP1
GeneAlias

CASP1 IL1BC IL1BCE
Unigene

Hs.2490;
Swiss Prot

P29466
Weight

10kDa
Datasheet
Msds
Properties

If you buy Antibodies supplied by Affinity Biosciences they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Description

Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
French translation

anticorps

Name

Models, Chemical
Concept

Scope note: Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
Tree numbers
- E05.599.495