TG101348

• Catalog number
  2314-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)ethoxy)phenylamino)pyrimidin-4-ylamino)benzenesulfonamide; SAR302503
• Description
  TG101348 is a potent, and selective inhibitor of JAK2 (IC₅₀ = 3 nM). It has a 35- and 334-fold selectivity over JAK3 and JAK1, respectively.
• CAS Number
  936091-26-8
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₇H₃₆N₆O₃S
• Molecular Weight
  524.68
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (~100 mg/ml) or Ethanol (~ 20 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent JAK2 inhibitor
• Storage Condition
  -20 ̊C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD09038564
• PubChem CID
  16722836
• PubChem CID Link
• SMILES
  CC1=CN=C(N=C1NC2=CC(=CC=C2)S(=O)(=O)NC(C)(C)C)NC3=CC=C(C=C3)OCCN4CCCC4
• InChi
  InChI=1S/C27H36N6O3S/c1-20-19-28-26(30-21-10-12-23(13-11-21)36-17-16-33-14-5-6-15-33)31-25(20)29-22-8-7-9-24(18-22)37(34,35)32-27(2,3)4/h7-13,18-19,32H,5-6,14-17H2,1-4H3,(H2,28,29,30,31)
• InChi Key
  JOOXLOJCABQBSG-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  TG101348  
• Short name
  TG101348
• Alternative name
  TG101348

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