TG101348
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Catalog number2314-1
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PricePlease ask
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Size1 mg
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Alternative_nameN-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)ethoxy)phenylamino)pyrimidin-4-ylamino)benzenesulfonamide; SAR302503
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DescriptionTG101348 is a potent, and selective inhibitor of JAK2 (IC₅₀ = 3 nM). It has a 35- and 334-fold selectivity over JAK3 and JAK1, respectively.
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CAS Number936091-26-8
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₇H₃₆N₆O₃S
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Molecular Weight524.68
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (~100 mg/ml) or Ethanol (~ 20 mg/ml)
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HandlingProtect from air and light
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Tag LineA potent JAK2 inhibitor
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Storage Condition-20 ̊C
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Shipping Conditiongel pack
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Shelf Life36 months
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MDL NumberMFCD09038564
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PubChem CID16722836
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SMILESCC1=CN=C(N=C1NC2=CC(=CC=C2)S(=O)(=O)NC(C)(C)C)NC3=CC=C(C=C3)OCCN4CCCC4
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InChiInChI=1S/C27H36N6O3S/c1-20-19-28-26(30-21-10-12-23(13-11-21)36-17-16-33-14-5-6-15-33)31-25(20)29-22-8-7-9-24(18-22)37(34,35)32-27(2,3)4/h7-13,18-19,32H,5-6,14-17H2,1-4H3,(H2,28,29,30,31)
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InChi KeyJOOXLOJCABQBSG-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameTG101348
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Alternative nameTG101348
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