XRCC3 (DNA Replication, Repair and Recombination Factor)
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Catalog number
GEN600597
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Price
Please ask
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Size
100ul
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Also known as
XRCC3
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Other names
XRCC3; DNA repair protein XRCC3; DNA repair protein XRCC3; OTTHUMP00000240458; X-ray repair cross-complementing protein 3; X-ray repair complementing defective repair in Chinese hamster cells 3; X-ray repair cross-complementing protein 3
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
XRCC3; XRCC3; CMM6; N/A
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Gene name synonims
XRCC3; XRCC3; CMM6; N/A
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Other gene names
XRCC3; XRCC3; CMM6; N/A
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG1
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Clone
3C191
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Host organism
Mouse (Mus musculus)
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Source organism
Human (Homo sapiens)
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Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
Specific for human XRCC3. It does not detect Rad51B, Rad51D, Rad51C, Rad51 or XRCC2 in Western blot analysis. ; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
Ascites Ascities
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Form Appearance
Supplied as ascites
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Concentration
N/A
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Storage and shipping
Store the antibody at -20 degrees Celsius.
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Tested applications
Western Blot (WB)
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Description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
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Test
Replication factor subunits and DNA replication proteins are found in DNA replication complexes like GINS, MCM,.. and replication initiators producing two identical replicas of DNA from one original DNA molecule. This process occurs in all living organisms and is the basis for biological inheritance. DNA is made up of a double helix of two strands, and each strand of the original DNA molecule gene serves as a template for the production of the complementary strand, a process referred to as semiconservative replication. Cellular proofreading and error-checking mechanisms ensure near perfect fidelity for DNA replication of genes.
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Gene target
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Gene symbol
XRCC3, PRKDC, HLA-DOA
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Short name
XRCC3 (DNA , Repair Recombination Factor)
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Technique
dna
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Alternative name
Anti-XRCC3 (DNA Replication, Repair and Recombination Factor)
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Alternative to gene target
X-ray repair complementing defective repair in Chinese hamster cells 3, CMM6, XRCC3 and IDBG-22058 and ENSG00000126215 and 7517, crossover junction endodeoxyribonuclease activity, nuclei, Xrcc3 and IDBG-173748 and ENSMUSG00000021287 and 74335, XRCC3 and IDBG-635474 and ENSBTAG00000009966 and 768244
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Gene info
Gene info
Gene info
MeSH Data
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Name
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Concept
Scope note:
A technique which uses synthetic oligonucleotides to direct the cell's inherent DNA repair system to correct a mutation at a specific site in an episome or chromosome.
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Tree numbers
- E02.095.301.500
- E05.393.420.301.500
- E05.393.420.601.575.500
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Qualifiers
legislation & jurisprudence, ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data
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