Human DNA repair protein XRCC3 (XRCC3)

Description

Recombinant Human DNA repair protein XRCC3(XRCC3) expressed in E.coli
Specifications

Uniprot ID: O43542; Host: Homo sapiens (Human); Expression system: E.coli; Expression region: 1-316aa; Sequence information: Full Length; Tag: N-terminal 6xHis-SUMO-tagged; Purity: Greater than 90% as determined by SDS-PAGE.
Additional_information

MW: 50.8 kDa; Buffer composition: Tris-based buffer with 50% glycerol.
Storage_and_shipping

Shipped on ice packs (+4°C). The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. Repeated freezing and thawing should be avoided. Store working aliquots at 4°C for up to one week.
Notes

For research use only.
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Gene target

DNA repair protein XRCC3 XRCC3
Gene symbol

XRCC3, PRKDC, HLA-DOA
Short name

DNA repair protein XRCC3 (XRCC3)
Technique

dna
Species

Human, Humans
Alternative name

H. sapiens Desoxyribonucleic acid repair protein X-ray repair complementing defective repair in Chinese hamster cells 3 (X-ray repair complementing defective repair in Chinese hamster cells 3)
Alternative to gene target

X-ray repair complementing defective repair in Chinese hamster cells 3, CMM6, XRCC3 and IDBG-22058 and ENSG00000126215 and 7517, crossover junction endodeoxyribonuclease activity, nuclei, Xrcc3 and IDBG-173748 and ENSMUSG00000021287 and 74335, XRCC3 and IDBG-635474 and ENSBTAG00000009966 and 768244

Identity

HGNC:12830
Gene

XRCC3
Long gene name

X-ray repair cross complementing 3
Synonyms gene name
- X-ray repair complementing defective repair in Chinese hamster cells 3
Synonyms name
- RAD51-like
GenBank acession
- AF035586
Locus

14q32.33
Discovery year

1995-08-11
Entrez gene record

7517
Pubmed identfication
- 7603995
RefSeq identity
- NM_005432
VEGA ID

OTTHUMG00000169228

Name

Targeted Gene Repair
Concept

Scope note: A technique which uses synthetic oligonucleotides to direct the cell's inherent DNA repair system to correct a mutation at a specific site in an episome or chromosome.
Tree numbers
- E02.095.301.500
- E05.393.420.301.500
- E05.393.420.601.575.500
Qualifiers

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