LSD1 antibody
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Catalog numberGEN533091
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PricePlease ask
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Size100ul
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Also known asLSD1
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Other namesLSD1; N/A
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CategoryAntibodies
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SubcategoryMnoclonal antibodies
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Gene nameLSD1
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Gene name synonimsN/A
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Other gene namesN/A
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ClonalityMonoclonal
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Immunoglobulin isotypeIgG1
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Clone1B2E5
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Host organismMouse (Mus musculus)
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Species reactivityHuman (Homo sapiens), Mouse (Mus musculus), Monkey; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivityN/A; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification methodN/A
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Form AppearanceSupplied as a liquid in ascitic fluid containing 0.03% sodium azide.
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Concentration1.0 mg/ml
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Storage and shippingFor optimal storage conditions, keep the antibody at +4°C. Temperature variations in the range 1°C to 9°C are tolerable. for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
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Tested applicationsELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
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PropertiesIf you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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GeneLysine-specific demethylase 1 (LSD1), the first identified histone demethylase, was belonged to the superfamily of the Flavin adenine dinucleotide (FAD)-dependent amine oxidases. LSD1 specifically demethylates mono- or dimethylated dimethylated histone H3 lysine4 (H3K4) and H3 lysine 9 (H3K9) via a redox process. Recently evidences showed that LSD1 played an important role in a broad spectrum of biological processes, including cell proliferation, adipogenesis, spermatogenesis, chromosome segregation and embryonic development. Furthermore, LSD1 also could promote progress of tumor by inhibiting the tumor suppressor activity of p53. To date, as a potential drug for discovering anti-tumor drugs, the medical significance of LSD1 inhibitors have been greatly appreciated. Here, we reviewed the remarkable progress being made in understanding of LSD1, mainly on its structure, basic function and medical application in tumor therapy.
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French translationanticorps
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Gene target
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Gene symbolKDM1A
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Short nameLSD1 antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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Alternative nameAnti-LSD1 antibody
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namelysine demethylase 1A
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Synonyms gene
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Synonyms gene name
- amine oxidase (flavin containing) domain 2
- lysine (K)-specific demethylase 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-02-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MicroRNA protein coding host genes
- Lysine demethylases
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data