LSD1 antibody
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Catalog number10R-1914
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PricePlease ask
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Size100 µl
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CategoryPrimary Antibody
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Antibody SubtypeMonoclonal Antibodies
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Area of researchProteases, Inhibitors, & Enzymes
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Type of ImmunogenLSD1 antibodies were raised in Mouse using a purified recombinant fragment of human LSD1 expressed in E. coli ..
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Raised inMouse
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Cross ReactivityHuman, Mouse, Monkey
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IsotypesIgG1
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Clone1B2E5
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Concentration1.0 mg/ml
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Form BufferProvided as a liquid in ascitic fluid containing 0.03% NaN3.
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StorageStore at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
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Shipping conditionsBlue Ice
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Tested forELISA; IHC; WB
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Usage RecommendationsELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000
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PropertiesIf you buy Antibodies supplied by fitzgerald they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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GeneLysine-specific demethylase 1 (LSD1), the first identified histone demethylase, was belonged to the superfamily of the Flavin adenine dinucleotide (FAD)-dependent amine oxidases. LSD1 specifically demethylates mono- or dimethylated dimethylated histone H3 lysine4 (H3K4) and H3 lysine 9 (H3K9) via a redox process. Recently evidences showed that LSD1 played an important role in a broad spectrum of biological processes, including cell proliferation, adipogenesis, spermatogenesis, chromosome segregation and embryonic development. Furthermore, LSD1 also could promote progress of tumor by inhibiting the tumor suppressor activity of p53. To date, as a potential drug for discovering anti-tumor drugs, the medical significance of LSD1 inhibitors have been greatly appreciated. Here, we reviewed the remarkable progress being made in understanding of LSD1, mainly on its structure, basic function and medical application in tumor therapy.
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French translationanticorps
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Gene target
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Gene symbolKDM1A
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Short nameLSD1 antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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Alternative nameMouse monoclonal LSD1 antibody
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namelysine demethylase 1A
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Synonyms gene
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Synonyms gene name
- amine oxidase (flavin containing) domain 2
- lysine (K)-specific demethylase 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-02-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MicroRNA protein coding host genes
- Lysine demethylases
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data