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Products_type
Antibody
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Products_short_name
[Estrogen Receptor Alpha (ESR1)]
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Products_name_syn
[Estrogen Receptor Alpha (ESR1), Purified, (polyclonal), (Rabbit IgG); Purified Rabbit Anti-Human/Mouse Estrogen Receptor 1 Polyclonal Antibody]
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Other_names
[estrogen receptor alpha]
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Products_gene_name
[ESR1]
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Clonality
Polyclonal
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Reactivity
Human
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Specificity
Estrogen Receptor Alpha (This antibody is specific for the human Estrogen receptor-alpha, isoform 1, 3 and 4. It is also specific for mouse and rat ESR1.)
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Form
Purified
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Storage_stability
Store at + 4 degree C. For long term storage, aliquot and freeze unused portion at -20 degree C in volumes appropriate for single usage. Avoid freeze/thaw cycles.
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Tested_application
ELISA (EIA), Western Blot (WB)
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Description
The Anti- Estrogen Receptor Alpha (ESR1), Purified, (polyclonal), (Rabbit IgG) is a α- or alpha protein sometimes glycoprotein present in blood. This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Test
MyBioSource supplies antibodies that are for research of human proteins.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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About
Immunoglobulin gamma, IgG, mouse monoclonal H&L chain clones or rabbit, goat polyclonal antibodies have 4 parts. There are 2 heavy chains, 2 light chains. The IgG antibody has 2 antigen binding sites. They represent 70% or more of serum antibodies. This antibody can be antigen purified or protein A or G purified. For storage sodium azide is added or you can call us to request azide free antibody preparations. These will need colder storage temperatures. Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Group
Polyclonals and antibodies
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Latin name
Oryctolagus cuniculus
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Gene target
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Gene symbol
ESR1
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Short name
Anti- Estrogen Receptor Alpha (ESR1), Purified, (polyclonal), (Rabbit IgG)
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Technique
anti-Human, Polyclonal, purified, Rabbit, anti-, anti, IgG, antibody to, antibodies, antibodies against human proteins, IgGs, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope. purifications
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Host
Rabbit, Rabbits
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Isotype
Rabbit IgG, IgG
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Species
Human, Humans
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Alternative name
Antibody tohuman Estrogen Receptor a (ESR1), enriched, (polyclonal), (production species: rabbit Immunoglobulin G)
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Alternative technique
polyclonals, pure, rabbit-anti, antibodies, immunoglobulins
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