Rabbit anti Estrogen Receptor alpha (ER-alpha) Polyclonal Antibody

• Catalog number
  MBS460118
• Price
  Please ask
• Size
  5x0.1 mg

• Products_type
  Antibody
• Products_short_name
  [Estrogen Receptor alpha (ER-alpha)]
• Products_name_syn
  [Estrogen receptor 1; ESR1]
• Products_gene_name
  [ER-alpha]
• Clonality
  Polyclonal
• Reactivity
  Human, Mouse, Rat
• Specificity
  This antibody recognizes ~67 kDa of human estrogen receptor. This antibody reacts with human. The other species are not tested.
• Purity
  Purified by Epitope Affinity Purification
• Form
  Supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
• Storage_stability
  The antibodies are stable for 12 months from date of receipt when stored at -20 degree C. The antibodies can be stored at 2 degree C - 8 degree C for one month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
• Tested_application
  ELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
• Description
  The Rabbit anti Estrogen Receptor alpha (ER-alpha) Polyclonal Antibody is a α- or alpha protein sometimes glycoprotein present in blood. This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Properties
  If you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus
• French translation
  anticorps

• Gene target
  Estrogen   Receptor   alpha   ER-alpha  
• Gene symbol
  EREG, MAN1B1, ESR2, ESR1
• Short name
  Rabbit anti Estrogen Receptor alpha (ER-alpha) Polyclonal Antibody
• Technique
  Polyclonal, Antibody, Rabbit, anti, antibody to, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Host
  Rabbit, Rabbits
• Isotype
  IgG
• Alternative name
  production species: rabbit antibody to Estrogen Receptor a (ER-a) polyclonal (antibody to-)
• Alternative technique
  polyclonals, antibodies, rabbit-anti

Gene info

• Identity
  HGNC:3443
• Gene
  EREG
• Long gene name
  epiregulin
• Synonyms
  • ER
• GenBank acession
  • D30783
• Locus
  4q13.3
• Discovery year
  1998-02-11
• Entrez gene record
  2069
• Pubmed identfication
  • 9337852
• VEGA ID
  OTTHUMG00000130005

Gene info

• Identity
  HGNC:6823
• Gene
  MAN1B1
• Long gene name
  mannosidase alpha class 1B member 1
• Synonyms gene name
  • mannosidase, alpha, class 1B, member 1
• Synonyms
  • MANA-ER
  • MRT15
  • ERManI
• Synonyms name
  • endoplasmic reticulum alpha-mannosidase 1
  • alpha 1,2-mannosidase
  • endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase 1
  • ER alpha 1,2-mannosidase
  • Man9GlcNAc2-specific processing alpha-mannosidase
  • endoplasmic Reticulum Class I alpha-mannosidase
• GenBank acession
  • AF145732
• Locus
  9q34.3
• Discovery year
  1999-09-28
• Entrez gene record
  11253
• Pubmed identfication
  • 10409699
  • 10521544
• RefSeq identity
  • NM_016219
• Classification
  • Mannosidases alpha class 1
• VEGA ID
  OTTHUMG00000020978

Gene info

• Identity
  HGNC:3468
• Gene
  ESR2
• Long gene name
  estrogen receptor 2
• Synonyms gene name
  • estrogen receptor 2 (ER beta)
• Synonyms
  • NR3A2
  • Erb
  • ER-beta
• Synonyms name
  • ER beta
  • estrogen receptor beta
  • oestrogen receptor beta
  • nuclear receptor subfamily 3 group A member 2
• GenBank acession
  • X99101
• Locus
  14q23.2-q23.3
• Discovery year
  1997-01-17
• Entrez gene record
  2100
• Pubmed identfication
  • 8769313
• Classification
  • Estrogen receptors
• VEGA ID
  OTTHUMG00000141306

Gene info

• Identity
  HGNC:3467
• Gene
  ESR1
• Long gene name
  estrogen receptor 1
• Synonyms gene
  • ESR
• Synonyms
  • NR3A1
  • Era
  • ER-alpha
• Synonyms name
  • nuclear receptor subfamily 3 group A member 1
  • estrogen receptor alpha
  • oestrogen receptor alpha
  • E2 receptor alpha
• GenBank acession
  • X03635
• Locus
  6q25.1-q25.2
• Discovery year
  2001-06-22
• Entrez gene record
  2099
• Pubmed identfication
  • 3754034
• RefSeq identity
  • NM_000125
• Classification
  • Estrogen receptors
• VEGA ID
  OTTHUMG00000016103
• Locus Specific Databases
  • LRG_992

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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