Sonic Hedgehog (SHH), murine recombinant

• Catalog number
  7884-1000
• Price
  Please ask
• Size
  1 mg

• Synonyms
  SHH; HHG1; HLP3; HPE3; SMMCI, Sonic hedgehog
• Alternative_names
  SHH; HHG1; HLP3; HPE3; SMMCI, Sonic hedgehog
• Description
  Hedgehog signaling pathway ligand involved in regulating vertebrate organogenesis
• Recombinant
  Yes
• Source
  E. coli
• Purity by SDS PAGE
  ≥97%
• Assay
  SDS-PAGE
• Purity
  ≥97%
• Molecular Weight
  19.8 kDa
• Storage Temp
  -20°C
• Shipping
  Gel pack
• Shelf Life
  12 months
• Appearance
  Lyophilized protein
• Physical form description
  Lyophilized from a 10 mM sodium phosphate buffer (pH 7.5)
• Reconstitution Instructions
  When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile H₂O to a concentration of 0.1-0.5 mg/ml, which can be further diluted into other aqueous solutions.
• Background Information
  Recombinant Mouse Sonic Hedgehog is a member of a small group of secreted proteins that are essential for development in both vertebrates and invertebrates. Three mammalian hedgehog genes (sonic, desert, Indian) share about 60% homology. The Mouse Sonic Hedgehog is 99% homologous to the human gene. Cysteine at position 25 has been substituted with Ile. Mouse SHH is a non-glycosylated polypeptide consisting of 176 amino acids with a molecular weight of 19,800 Da.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Sonic   Hedgehog   SHH   murine  
• Gene symbol
  SHH
• Short name
  Sonic Hedgehog (SHH), murine recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Alternative name
  Sonic Hedgehog (sonic hedgehog), murine Rec.
• Alternative technique
  rec
• Alternative to gene target
  sonic hedgehog, HHG1 and HLP3 and HPE3 and MCOPCB5 and SMMCI and TPT and TPTPS, SHH and IDBG-50464 and ENSG00000164690 and 6469, laminin-1 binding, nuclei, Shh and IDBG-144309 and ENSMUSG00000002633 and 20423, SHH and IDBG-638249 and ENSBTAG00000024552 and

Gene info

• Identity
  HGNC:10848
• Gene
  SHH
• Long gene name
  sonic hedgehog signaling molecule
• Synonyms gene
  • HPE3
  • HLP3
• Synonyms gene name
  • sonic hedgehog (Drosophila) homolog
• Synonyms
  • HHG1
  • SMMCI
  • TPT
  • TPTPS
  • MCOPCB5
• Locus
  7q36.3
• Discovery year
  1995-03-10
• Entrez gene record
  6469
• Pubmed identfication
  • 7590746
• RefSeq identity
  • NM_000193
• Classification
  • Hedgehog signaling molecule family
• VEGA ID
  OTTHUMG00000151349

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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