Plasma Kallikrein Activity Assay Kit (Colorimetric)

• Catalog number
  K997-100
• Price
  Please ask
• Size
  100 assays

• Description
  Highly Sensitive, minimum sample preparation required
• Summary
  • Detection method- Colorimetric (Absorbance 405 nm) • Applications- Measurement of Plasma Kallikrein activity in plasma and purified/crude enzyme preparations
• Detection Method
  Colorimetric (Absorbance 405 nm)
• Species Reactivity
  Mammalians
• Applications
  Measurement of Plasma Kallikrein activity in plasma samples and purified/crude enzyme preparations
• Sample Type
  Plasma and Purified enzyme
• Features Benefits
  • Simple, rapid & convenient assay to measure Plasma Kallikrein • Includes Positive Control and Plasma Kallikrein and Plasma Kallikrein Inhibitors
• Storage Conditions
  -20°C
• Shipping Conditions
  gel pack
• Shelf life
  12 months
• Background
  Plasma Prekallikrein (EC 3.4.21.34), is the glycosylated single chain zymogen precursor of the plasma serine protease Kallikrein. It circulates with kininogen and is activated by Factor XIIa to Kallikrein in the intrinsic coagulation pathway. Kallikrein activates plasminogen in fibrinolysis and cleaves kininogen in the bradykinin system of vasodilation. Prekallikrein deficiency is rare and causes increased activated partial thromboplastin time. Elevated plasma Prekallikrein is associated with diabetes and cardiovascular disease. Plasma Kallikrein inhibitors have been proposed as drugs to manage Hereditary Angioedema. BioVision’s Plasma Kallikrein Activity Assay Kit utilizes the ability of active Plasma Kallikrein to cleave a synthetic pNA-based peptide substrate to release pNA (OD405 nm), which can be easily quantified using a microplate reader. The Plasma Kallikrein Specific Inhibitor (PKSI) selectively inhibits the ability of Plasma Kallikrein to the cleave the synthetic substrate. The kit is easy-to-use and can detect PK activity of Purified Plasma Kallikrein and Plasma Samples
• Data Sheet Link
• Test
  Biovision supplies other types of Assays as 1.
• Properties
  Colorimetric assays or detection use UV absorption or enzymatic color reaction.

• Gene target
  Plasma   Kallikrein   Activity   Kit  
• Short name
  Plasma Kallikrein Activity Assay Kit (Colorimetric)
• Technique
  colorimetric, Assay, assays, colorimetry
• Host
  Assay
• Alternative name
  Plasma Kallikrein Activity test reagent (colorimetry)
• Alternative technique
  assays, arrays, kits
• Alternative to gene target
  v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832

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