Recombinant Human SerpinI2 Protein (His tag) 100µg

  • Catalog number
    PKSH031311-100µg
  • Price
    Please ask
  • Size
    100µg
  • Synonym
    MEPI;PANCPIN;PI14;TSA2004
  • Activity
    NA
  • Sequence
    Met 1-Leu 405
  • Fusion tag
    C-His
  • Accession
    NP_006208.1
  • Expressed Host
    HEK293 Cells
  • Shipping
    In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
  • Purity
    >90 % as determined by SDS-PAGE
  • Endotoxin
    <1.0 EU per µg as determined by the LAL method
  • Stability and Storage
    Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Mol Mass
    45.5 kDa
  • AP Mol Mass
    45-55 kDa
  • Formulation
    Lyophilized from sterile PBS, pH 7.4
  • Reconstitution
    Please refer to it for detailed information.
  • Background
    Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhibit chymotrypsin-like serine proteases (serine protease inhibitors). Over 1000 serpins have been identified. Serpin-I2, also known as myoepithelium-derived serine protease inhibitor, Pancreas-specific protein TSA2004, Peptidase inhibitor 14, PI14, SERPINI2 and MEPI, is a secreted protein which belongs to the serpin family. It is expressed in pancreas and adipose tissues. SERPINI2 deficiency directly results in the acinar cell apoptosis and malabsorption.
  • Conjugation
    histidine
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
    SerpinI2   Protein   His   tag   100µg  
  • Short name
    Recombinant SerpinI2 Protein (His tag) 100µg
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
  • Label
    His
  • Species
    Human, Humans
  • Alternative name
    Rec. H. sapiens serpin peptidase inhibitor, clade I (pancpin), member 2 Protein (histidine detection labelled) 100µg
  • Alternative technique
    rec
  • Alternative to gene target
    serpin peptidase inhibitor, clade I (pancpin), member 2, MEPI and PANCPIN and PI14 and TSA2004, SERPINI2 and IDBG-63921 and ENSG00000114204 and 5276, protein binding, Extracellular, Serpini2 and IDBG-152263 and ENSMUSG00000034139 and 67931, SERPINI2 and IDBG-636843 and ENSBTAG00000011423 and 519219
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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