LAP2 (Lamina Associated Polypeptide 2, Thymopoietin, TMPO) Antibody

• Catalog number
  GEN602293
• Price
  Please ask
• Size
  200ul

• Also known as
  LAP2
• Other names
  Leucine aminopeptidase 2; N/A
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  N/A
• Gene name synonims
  N/A
• Other gene names
  N/A
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG
• Clone
  4i386
• Host organism
  Hamster
• Source organism
  Rat (Rattus norvegicus)
• Species reactivity
  Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Detects Lamin Associated Polypeptide (LAP) 2 from various rat tissues but does not crossreact with LAP 1A, 1B & 1C. Recognizes a single 53kD protein representing LAP 2 in rat liver nuclear envelope fractions.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  IgG fraction.
• Form Appearance
  Supplied as a liquid in PBS with 0.05% sodium azide.
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze the antibody should be stored at -20 degrees Celsius.. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. Prior to use, briefly centrifuge the original vial after thawing and before lid. If further dilution(s) are needed, they can be done with the appropriate assay buffer.
• Tested applications
  Western Blot (WB), Immunoprecipitation (IP), Immunofluorescence (IF)
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Gene
  Thymopoietin I and II are proteins involved in the induction of CD90 in the thymus. The thymopoetin (TMPO) gene encodes three alternatively spliced mRNAs encoding proteins of 75 kDa (alpha), 51 kDa (beta) and 39 kDa (gamma) which are ubiquitously expressed in all cells. The human TMPO gene maps to chromosome band 12q22 and consists of eight exons. TMPO alpha is present diffusely expressed with the cell nucleus while TMPO beta and gamma are localized to the nuclear membrane. TMPO beta is a human homolog of the murine protein LAP2. LAP2 plays a role in the regulation of nuclear architecture by binding lamin B1 and chromosomes. This interaction is regulated by phosphorylation during mitosis. Given the nuclear localization of the three TMPO isoforms, it is unlikely that these proteins play any role in CD90 induction.
• French translation
  anticorps

• Gene target
  LAP2   Lamina   Associated   Polypeptide   Thymopoietin   TMPO  
• Gene symbol
  TMPO, TMPO-AS1, ERBIN
• Short name
  LAP2 (Lamina Associated Polypeptide 2, Thymopoietin, TMPO) Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  Anti-LAP2 (Lamina Associated Polypeptide 2, Thymopoietin, TMPO)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:11875
• Gene
  TMPO
• Long gene name
  thymopoietin
• Synonyms
  • TP
  • LAP2
  • LEMD4
• Synonyms name
  • LEM domain containing 4
• Locus
  12q23.1
• Discovery year
  1994-11-08
• Entrez gene record
  7112
• Pubmed identfication
  • 7517549
• RefSeq identity
  • NM_003276
• Classification
  • LEM domain containing
• VEGA ID
  OTTHUMG00000170210
• Locus Specific Databases
  • LRG_443

Gene info

• Identity
  HGNC:44158
• Gene
  TMPO-AS1
• Long gene name
  TMPO antisense RNA 1
• Synonyms gene name
  • TMPO antisense RNA 1 (non-protein coding)
• Locus
  12q23.1
• Discovery year
  2012-06-30
• Entrez gene record
  100128191
• Pubmed identfication
  • 31230752
• RefSeq identity
  • NR_027157
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000170209

Gene info

• Identity
  HGNC:15842
• Gene
  ERBIN
• Long gene name
  erbb2 interacting protein
• Synonyms gene
  • ERBB2IP
• Synonyms gene name
  • erbb2-interacting protein
• Synonyms
  • LAP2
• Synonyms name
  • densin-180-like protein
  • ERBB2-interacting protein
• Locus
  5q12.3
• Discovery year
  2001-06-18
• Entrez gene record
  55914
• Pubmed identfication
  • 10574462
  • 10878805
• RefSeq identity
  • NM_018695
• Classification
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000097808

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products