Lymphocyte Activation Gene 3 Antibody, ALEXA FLUOR 488
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Catalog numberbs-2646R-A488
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PricePlease ask
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Size100ul
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Long nameLymphocyte Activation Gene 3 Antibody, ALEXA FLUOR 488 Conjugated
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Also known asAnti-Lymphocyte Activation Gene 3 PAb ALEXA FLUOR 488
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CategoryConjugated Primary Antibodies
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Conjugated withALEXA FLUOR® 488
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target AntigenLymphocyte Activation Gene 3
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SpecificityThis is a highly specific antibody against Lymphocyte Activation Gene 3.
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ModificationUnmodified
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Modification SiteNone
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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Immunogen range210-260/525
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Subcellular locationExtracellular
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Lymphocyte Activation Gene 3
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Gene ID Number297596
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Swiss ProtQ5BK54
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Tested applicationsFCM, IF(IHC-P), IF(ICC)
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Recommended dilutionsFCM(1:20-100), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)
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CrossreactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the antigenLymphocyte-activation protein 3 (LAG-3), also known as CD223, belongs to the immunoglobulin superfamily and contains 4 extracellular Ig-like domains. LAG-3 binds to HLA class-II antigens and is involved in lymphocyte activation. It is found on the cell surface of activated NK and T-lymphocytes. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG-3 to CD4.
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PurificationPurified by Protein A.
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Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission499nm/519nm
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SynonymsCD223; Lymphocyte activation gene 3 protein; LAG-3; Lag3
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PropertiesFor facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-Lymphocyte Activation Gene 3 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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ConjugationAlexa Fluor
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DescriptioncDNA genes are a locus (or region) of DNA for functional transcript RNA or protein. An ELISA is used to detect the expressed protein in biological fluids, serum, saliva.
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French translationanticorps
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Gene target
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Gene symbolLAG3
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Short nameAnti-Lymphocyte Activation Gene 3
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Techniqueactivation, Antibody, antibodies against human proteins, antibodies for
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IsotypeImmunoglobulin G (IgG)
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LabelALEXA FLUOR 488
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Alternative nameLymphocyte Activation Gene 3 Antibody, ALEXA FLUOR 488
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Alternative techniqueantibodies
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Tissuelymphocyte
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Gene info
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Identity
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Gene
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Long gene namelymphocyte activating 3
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Synonyms gene name
- lymphocyte-activation gene 3
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Synonyms
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Locus
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Discovery year1991-06-03
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin like domain containing
- CD molecules
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data