- Catalog numberbs-2646R-A594
- Product nameLymphocyte Activation Gene 3 Antibody, ALEXA FLUOR 594
- Size100ul
- PriceAsk For Price
- Short nameAnti-Lymphocyte Activation Gene 3
- Long nameLymphocyte Activation Gene 3 Antibody, ALEXA FLUOR 594 Conjugated
- Also known asAnti-Lymphocyte Activation Gene 3 PAb ALEXA FLUOR 594
- CategoryConjugated Primary Antibodies
- Conjugated withALEXA FLUOR® 594
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenLymphocyte Activation Gene 3
- SpecificityThis is a highly specific antibody against Lymphocyte Activation Gene 3.
- ModificationUnmodified
- Modification SiteNone
- ClonalityPolyclonal
- ClonePolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- Immunogen range210-260/525
- Subcellular locationExtracellular
- SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Lymphocyte Activation Gene 3
- Gene ID Number297596
- Swiss ProtQ5BK54
- Tested applicationsFCM, IF(IHC-P), IF(ICC)
- Recommended dilutionsFCM(1:20-100), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)
- CrossreactivityHuman, Mouse, Rat
- Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Background of the antigenLymphocyte-activation protein 3 (LAG-3), also known as CD223, belongs to the immunoglobulin superfamily and contains 4 extracellular Ig-like domains. LAG-3 binds to HLA class-II antigens and is involved in lymphocyte activation. It is found on the cell surface of activated NK and T-lymphocytes. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG-3 to CD4.
- PurificationPurified by Protein A.
- Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
- Excitation emission590nm/617nm
- SynonymsCD223; Lymphocyte activation gene 3 protein; LAG-3; Lag3
- Gene targetLymphocyte Activation Gene 3
- Identity:HGNC:6476
- Gene:LAG3
- Long gene name:lymphocyte activating 3
- Synonyms gene name:lymphocyte-activation gene 3
- Synonyms:CD223
- Discovery year:1991-06-03
- Entrez gene record:3902
- RefSeq identity:NM_002286
- Classification:Immunoglobulin like domain containing, CD molecules
- VEGA ID:OTTHUMG00000169197
- Gene symbolLAG3
- isotype filter
- Immunoglobulin G IgG
- LabelALEXA FLUOR 594
- label filter
- ALEXA FLUOR 594
- technique filter
- activation
- Antibody
- Techniqueactivation, Antibody, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies
- Tissuelymphocyte
- tissue filter
- lymphocyte