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BAFF Receptor human recombinant

BAFF Receptor human recombinant is available 3 times from Biovision labs

4452-10 | BAFF Receptor, human recombinant size: 10 ug | 155.56 USD

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4452-1000 | BAFF Receptor, human recombinant size: 1 mg | 2,354.22 USD

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4452-50 | BAFF Receptor, human recombinant size: 50 ug | 284.89 USD

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Synonyms human BAFF Receptor, h-BAFF Receptor, rh-BAFF Receptor, recombinant human BAFF Receptor, recombinant BAFF Receptor
Alternative_names Tumor necrosis factor receptor superfamily member 13C, B-cell-activating factor receptor, BAFF receptor, Short name=BAFF-R, BLyS receptor 3, CD_antigen=CD268
Description A TNF receptor that specifically interacts with BAFF
Recombinant Yes
Source E. coli
Purity by SDS-PAGE ≥95%
Assay SDS-PAGE
Purity ≥95%
Biological activity Determined by its ability to block BAFF induced mouse splenocyte survival. The expected ED₅₀ for this effect is typically 1-5 µg/ml in the presence of 1 µg/ml human soluble BAFF.
Results 1-5 µg/ml
Molecular Weight 7.7 kDa
Storage Temp. -20°C
Shipping Gel pack
Shelf Life 12 months
Appearance Lyophilized protein
Physical form description Sterile filtered and lyophilized from a solution (1 mg/ml) containing 20 mM phosphate buffer, pH 8.0, and 500 mM NaCl.
Reconstitution Instructions Reconstitute in sterile H₂O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers or stored at 4°C for 1 week or –20°C for future use.
Background Information BAFF Receptor (BAFFR), a member of the TNFR superfamily, is highly expressed in spleen, lymph node, and resting B cells and to some extent in activated B cells, resting CD4+ cells and peripheral blood leukocytes. BAFFR is a type III transmembrane protein that binds with high specificity to BAFF (TNFSF13B). BAFFR/BAFF signaling plays a critical role in B cell survival and maturation. Recombinant human BAFFR is a 76 amino acid polypeptide (7.7 kDa) corresponding to the extraCellular portion of the full BAFFR protein.
Handling Centrifuge the vial prior to opening.
Usage For Research Use Only! Not to be used in humans
Properties Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional description The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
Additional source Recombinants or rec. proteins
Group recombinants
Gene targetBAFF Receptor
Short name BAFF Receptor, recombinant
Technique Recombinant
Species Human
Alternative name BAFF Receptor, H. sapiens recombinant
Alternative technique rec
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