KX-392 dihydrochloride

• Catalog number
  B2189-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  5-[4-[2-(4-Morpholinyl)ethoxy]phenyl]-N-(phenylmethyl)-2-pyridineacetamide hydrochloride; N-benzyl-2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)acetamide dihydrochloride
• Description
  KX-392 is a potent oral non-ATP competitive inhibitor of Src kinase and tubulin polymerization. KX2-391 shows steep dose-response curves against Huh7 (GI₅₀ = 9 nM), PLC/PRF/5 (GI₅₀ = 13 nM), Hep3B (GI₅₀ = 26 nM), and HepG2 (GI₅₀ = 60 nM), four hepatic cell cancer (HCC) cell lines.
• CAS Number
  1038395-65-1
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₆H₃₁Cl₂N₃O₃
• Molecular Weight
  504.45
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>50 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent inhibitor of Src kinase and tubulin polymerization
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  24989633
• PubChem CID Link
• SMILES
  C1COCCN1CCOC2=CC=C(C=C2)C3=CN=C(C=C3)CC(=O)NCC4=CC=CC=C4.Cl.Cl
• InChi
  InChI=1S/C26H29N3O3.2ClH/c30-26(28-19-21-4-2-1-3-5-21)18-24-9-6-23(20-27-24)22-7-10-25(11-8-22)32-17-14-29-12-15-31-16-13-29;;/h1-11,20H,12-19H2,(H,28,30);2*1H
• InChi Key
  CPTPOZGQCQXHJO-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  KX-392   dihydrochloride  
• Gene symbol
  XK, OR7E15P
• Short name
  KX-392 dihydrochloride
• Alternative name
  KX-392 dihydrochloride

Gene info

• Identity
  HGNC:12811
• Gene
  XK
• Long gene name
  X-linked Kx blood group
• Synonyms gene
  • NA
  • NAC
• Synonyms gene name
  • Kell blood group precursor (McLeod phenotype)
  • XK, Kell blood group complex subunit (McLeod syndrome)
  • neuroacanthocytosis
  • neurocanthocytosis
• Synonyms
  • XKR1
  • Kx
  • X1k
• Synonyms name
  • Kx antigen
  • McLeod syndrome
• GenBank acession
  • Z32684
• Locus
  Xp21.1
• Discovery year
  2001-06-22
• Entrez gene record
  7504
• Pubmed identfication
  • 8004674
  • 11761473
• RefSeq identity
  • NM_021083
• Classification
  • XK related family
  • Blood group antigens
• VEGA ID
  OTTHUMG00000033171
• Locus Specific Databases
  • Blood Group Antigen Mutation Database
  • Global Variome shared LOVD
  • LRG_812

Gene info

• Identity
  HGNC:8386
• Gene
  OR7E15P
• Long gene name
  olfactory receptor family 7 subfamily E member 15 pseudogene
• Synonyms gene
  • OR7E80P
  • OR7E42P
• Synonyms gene name
  • olfactory receptor, family 7, subfamily E, member 15 pseudogene
• Synonyms
  • OR11-392
  • OST001
• GenBank acession
  • AF065873
• Locus
  8p23.1
• Discovery year
  1998-11-09
• Entrez gene record
  8588
• Pubmed identfication
  • 9787077
• Classification
  • Olfactory receptors, family 7
• VEGA ID
  OTTHUMG00000165468

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