LSD1/AOF2 monoclonal antibody (1B2F2)
#
-
Catalog numberMBS565128
-
Price:
-
Size0.1 mg
-
-
Products_typeAntibody
-
Products_short_name[LSD1/AOF2]
-
Products_name_syn[LSD1/AOF2]
-
Other_names[Lysine-specific histone demethylase 1A; Lysine-specific histone demethylase 1A; lysine-specific histone demethylase 1A; lysine demethylase 1A; BRAF35-HDAC complex protein BHC110; Flavin-containing amine oxidase domain-containing protein 2]
-
Other_gene_names[KDM1A; KDM1A; AOF2; CPRF; KDM1; LSD1; BHC110; AOF2; KDM1; KIAA0601; LSD1]
-
ClonalityMonoclonal
-
Clone[1B2F2]
-
ReactivityHuman, Mouse, Rat
-
SpecificityRecognizes human, mouse and rat LSD1/AOF2.
-
PurityProtein G affinity purified.
-
FormLiquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
-
Storage_stabilityLong term storage: -20 degree C Avoid freeze/thaw cycles.
-
Tested_applicationWestern Blot (WB)
-
PropertiesIf you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
GeneLysine-specific demethylase 1 (LSD1), the first identified histone demethylase, was belonged to the superfamily of the Flavin adenine dinucleotide (FAD)-dependent amine oxidases. LSD1 specifically demethylates mono- or dimethylated dimethylated histone H3 lysine4 (H3K4) and H3 lysine 9 (H3K9) via a redox process. Recently evidences showed that LSD1 played an important role in a broad spectrum of biological processes, including cell proliferation, adipogenesis, spermatogenesis, chromosome segregation and embryonic development. Furthermore, LSD1 also could promote progress of tumor by inhibiting the tumor suppressor activity of p53. To date, as a potential drug for discovering anti-tumor drugs, the medical significance of LSD1 inhibitors have been greatly appreciated. Here, we reviewed the remarkable progress being made in understanding of LSD1, mainly on its structure, basic function and medical application in tumor therapy.
-
AboutMonoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
-
French translationanticorps
-
Gene target
-
Gene symbolKDM1A
-
Short nameLSD1/AOF2 monoclonal antibody (1B2F2)
-
TechniqueAntibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
-
HostMouse
-
IsotypeIgG1
-
Alternative nameLSD1/AOF2 monoclonal (antibody to-) (1B2F2)
-
Alternative techniqueantibodies
-
Gene info
-
Identity
-
Gene
-
Long gene namelysine demethylase 1A
-
Synonyms gene
-
Synonyms gene name
- amine oxidase (flavin containing) domain 2
- lysine (K)-specific demethylase 1
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2004-02-26
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- MicroRNA protein coding host genes
- Lysine demethylases
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data