4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione (GSK-3beta Inhibitor I, TDZD-8)

• Catalog number
  MBS6038974
• Price
  Please ask
• Size
  10 mg

• Other size
  please contact us to order other different size
• Description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme. A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3. In formulas, the group is often abbreviated Me. Such hydrocarbon groups occur in many organic compounds. It is a very stable group in most molecules. While the methyl group is usually part of a larger molecule, it can be found on its own in any of three forms anion, cation or radical. The anion has eight valence electrons, the radical seven and the cation six. All three forms are highly reactive and rarely observed,

• Gene target
  4-Benzyl-2-methyl-1   4-thiadiazolidine-3   5-dione   GSK-3beta   Inhibitor   TDZD-8  
• Gene symbol
  TRN-GTT2-8, KRTAP5-2, TRE-TTC8-2, SNORD114-8, TRQ-CTG8-2, KRTAP5-8, TRA-AGC8-2, RNU6-8, TRP-AGG2-8, TRX-CAT1-8
• Short name
  4-Benzyl-2-methyl-1 2 4-thiadiazolidine-3 5-dione (GSK-3beta Inhibitor I, TDZD-8)
• Alternative name
  4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione (GSK-3beta suppressor I, TDZD-8)

Gene info

• Identity
  HGNC:54715
• Gene
  TRN-GTT2-8
• Long gene name
  tRNA-Asn (anticodon GTT) 2-8
• Synonyms
  • tRNA-Asn-GTT-2-8
• Locus
  1q21.1
• Discovery year
  2019-12-06
• Entrez gene record
  100189127
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:23597
• Gene
  KRTAP5-2
• Long gene name
  keratin associated protein 5-2
• Synonyms
  • KRTAP5.2
  • KRTAP5-8
• GenBank acession
  • AB126071
• Locus
  11p15.5
• Discovery year
  2003-12-01
• Entrez gene record
  440021
• Pubmed identfication
  • 15144888
• RefSeq identity
  • NM_001004325
• Classification
  • Keratin associated proteins
• VEGA ID
  OTTHUMG00000165547

Gene info

• Identity
  HGNC:54204
• Gene
  TRE-TTC8-2
• Long gene name
  tRNA-Glu (TTC) 8-2
• Synonyms
  • tRNA-Glu-TTC-8-2
• Locus
  1p22.1
• Discovery year
  2019-03-28
• Classification
  • Low confidence cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:32996
• Gene
  SNORD114-8
• Long gene name
  small nucleolar RNA, C/D box 114-8
• Synonyms
  • 14q(II-8)
• Locus
  14q32.31
• Discovery year
  2006-09-26
• Entrez gene record
  767584
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003200.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:34716
• Gene
  TRQ-CTG8-2
• Long gene name
  tRNA-Gln (CTG) 8-2
• Synonyms gene
  • TRNAQ14
• Synonyms gene name
  • transfer RNA glutamine 14 (anticodon CUG)
  • transfer RNA-Gln (CTG) 8-2
• Synonyms
  • tRNA-Gln-CTG-8-2
• GenBank acession
  • HG983730
• Locus
  1q21.1
• Discovery year
  2008-08-29
• Entrez gene record
  100189154
• Classification
  • Low confidence cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:23603
• Gene
  KRTAP5-8
• Long gene name
  keratin associated protein 5-8
• Synonyms
  • KRTAP5.8
  • UHSKerB
  • KRTAP5-2
• GenBank acession
  • AB126077
• Locus
  11q13.4
• Discovery year
  2003-12-01
• Entrez gene record
  57830
• Pubmed identfication
  • 15144888
• RefSeq identity
  • NM_021046
• Classification
  • Keratin associated proteins
• VEGA ID
  OTTHUMG00000057571

Gene info

• Identity
  HGNC:34966
• Gene
  TRA-AGC8-2
• Long gene name
  tRNA-Ala (anticodon AGC) 8-2
• Synonyms gene
  • TRNAA39
• Synonyms gene name
  • transfer RNA alanine 39 (anticodon AGC)
  • transfer RNA-Ala (AGC) 8-2
• Synonyms
  • tRNA-Ala-AGC-8-2
• GenBank acession
  • HG983557
• Locus
  8q13.1
• Discovery year
  2008-08-29
• Entrez gene record
  100189398
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34285
• Gene
  RNU6-8
• Long gene name
  RNA, U6 small nuclear 8
• Synonyms
  • U6-8
• Locus
  14q12
• Discovery year
  2008-06-10
• Entrez gene record
  101954278
• Pubmed identfication
  • 12711679
• RefSeq identity
  • NR_104088
• Classification
  • Small nuclear RNAs

Gene info

• Identity
  HGNC:34862
• Gene
  TRP-AGG2-8
• Long gene name
  tRNA-Pro (anticodon AGG) 2-8
• Synonyms gene
  • TRNAP18
  • TRP-AGG2-6
• Synonyms gene name
  • transfer RNA proline 18 (anticodon AGG)
  • transfer RNA-Pro (AGG) 2-6
  • transfer RNA-Pro (AGG) 2-8
• Synonyms
  • tRNA-Pro-AGG-2-8
• GenBank acession
  • HG983983
• Locus
  16p13.3
• Discovery year
  2008-08-29
• Entrez gene record
  100189296
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34818
• Gene
  TRX-CAT1-8
• Long gene name
  tRNA-iMet (anticodon CAT) 1-8
• Synonyms gene
  • TRNAM14
  • TRX-CAT1-2
• Synonyms gene name
  • transfer RNA methionine 14 (anticodon CAU)
  • transfer RNA-iMet (CAT) 1-2
  • transfer RNA-iMet (CAT) 1-8
• Synonyms
  • tRNA-iMet-CAT-1-8
• Synonyms name
  • transfer RNA initiator methionine (CAT) 1-2
• GenBank acession
  • HG984137
• Locus
  17q25.3
• Discovery year
  2008-08-29
• Entrez gene record
  100189255
• Classification
  • Cytoplasmic transfer RNAs

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