anti- HDAC8 antibody

• Catalog number
  FNab03805
• Price
  Please ask
• Size
  2X100μg

• Form
  liquid
• Purification
  Immunogen affinity purified
• Purity
  ≥95% as determined by SDS-PAGE
• Storage
  PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
• Background
  Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.
• Immunogen
  histone deacetylase 8
• Synonyms
  HDACL1
• Calculated MW
  43 kDa
• Uniprot ID
  Q9BY41
• Specificity
  Human, Mouse, Rat
• Tested Application
  ELISA, WB, IHC
• Recommended dilution
  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Properties
  If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  HDAC8  
• Gene symbol
  HDAC8
• Short name
  anti- HDAC8 antibody
• Technique
  Antibody, anti, antibody to, antibodies against human proteins, antibodies for
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  antibody to- HDAC8 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:13315
• Gene
  HDAC8
• Long gene name
  histone deacetylase 8
• Synonyms gene
  • HDACL1
  • WTS
  • MRXS6
• Synonyms gene name
  • histone deacetylase-like 1
  • Wilson-Turner X-linked mental retardation syndrome
• Synonyms
  • RPD3
  • KDAC8
• GenBank acession
  • AF230097
• Locus
  Xq13.1
• Discovery year
  2000-11-28
• Entrez gene record
  55869
• Pubmed identfication
  • 10756090
  • 10922473
  • 22889856
• RefSeq identity
  • NM_018486
• Classification
  • Histone deacetylases, class I
• VEGA ID
  OTTHUMG00000021814
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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