Rabbit Anti Human HDAC8 Antibody-Non-conjugated

• Catalog number
  CSB-PA010244ESR1HU_100ul
• Price
  Please ask
• Size
  100ul

• Long name
  Rabbit Antibody against Human HDAC8, Non-conjugated
• Synonym name
  HDAC8 Human Antibody
• Species reactivity
  Human
• Tested applications recommended dilutions
  ELISA,IHC;Recommended dilution:IHC:1:20-1:200
• Conjugation
  Non-conjugated
• Antibody isotype
  IgG
• UniProt ID
  Q9BY41
• Format
  Liquid, diluted in buffer
• Buffer composition
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Purity
  >95%
• Purification method
  Antigen Affinity Purified Antibodies
• Antibody category
  Polyclonal Antibodies
• Immunogen type
  Recombinant human Histone deacetylase 8 protein (1-377AA)
• Immunogen species
  Human
• Alias
  HD8,HDACL1,HDAC8,CDA07
• Background
  Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility.
• Clonality
  Polyclonal antibody
• Shipping and storage
  HDAC8 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
• Properties
  If you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  Rabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus
• French translation
  anticorps

• Gene target
  HDAC8   Non-conjugated  
• Gene symbol
  HDAC8
• Short name
  Anti-HDAC8
• Technique
  anti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
• Host
  Rabbit, Rabbits
• Species
  Human, Humans
• Alternative name
  HDAC8 Antibody
• Alternative technique
  antibodies, rabbit-anti

Gene info

• Identity
  HGNC:13315
• Gene
  HDAC8
• Long gene name
  histone deacetylase 8
• Synonyms gene
  • HDACL1
  • WTS
  • MRXS6
• Synonyms gene name
  • histone deacetylase-like 1
  • Wilson-Turner X-linked mental retardation syndrome
• Synonyms
  • RPD3
  • KDAC8
• GenBank acession
  • AF230097
• Locus
  Xq13.1
• Discovery year
  2000-11-28
• Entrez gene record
  55869
• Pubmed identfication
  • 10756090
  • 10922473
  • 22889856
• RefSeq identity
  • NM_018486
• Classification
  • Histone deacetylases, class I
• VEGA ID
  OTTHUMG00000021814
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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