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anti-SIRT7 Antibody

anti-SIRT7 Antibody is available 1 time from Biovision labs

6107-50 | anti-SIRT7 Antibody size: SIRT7 Antibody | 326.73 USD

Catalog number 6107-50
Supplier Biovision
Price 326.73 USD
Size SIRT7 Antibody
1. Gene info
Identity 14935
Gene SIRT7
Long gene name sirtuin 7
Synonyms gene name
  • sirtuin (silent mating type information regulation 2, S.cerevisiae, homolog) 7
  • sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae)
GenBank acession
  • AF233395
Locus 17q25.3
Discovery year 2001-03-20
Entrez gene record 51547
Pubmed identfication
  • 10873683
  • 16618798
RefSeq identity
  • NM_016538
Classification
  • Sirtuins
Havana BLAST/BLAT OTTHUMG00000177957
Product images
    #0#.jpegSIRT7 Antibody
Target of this antibody: SIRT7
Alternative names of antibody target: SIR2; Sirtuin 7; Silent Information Regulator 7
Background information: The sirtuins represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs) and have been shown to catalyze a reaction that couples lysine deacetylation to the formation of nicotinamide and O-acetyl-ADP-ribose from NAD+ and the abstracted acetyl group. SIRT7 is a member of this family of proteins and is present in prokaryotes and eukaryotes. All SIR2-like proteins have a sirtuin core domain, which contains a series of sequence motifs conserved in organisms ranging from bacteria to humans. Bacterial, yeast, and mammalian sirtuins are able to metabolize NAD+ and several act as mono-ADP-ribosyltransferases. The enzymatic function of sirtuins is not yet completely understood but as mentioned above, recent reports of histone-activated SIR2-mediated NAD+ metabolism and NAD+-activated SIR2-mediated histone deacetylation sμggest a possible coupled reciprocal activation mechanism involving interactions of SIR2 with NAD+ and the N-ε-acetyl-lysine groups of acetylated histone.
Antibody host: Rabbit
Clonality of antibody: Polyclonal
Isotype: Rabbit IgG
This antibody reacts with: Human
Immunogene sequence: Human SIRT7 aa 35-51 and 361-377
Concentration of antibody: N/A
Form of antibody: Liquid
Formulation of this antibody: 50 µg of antibody in 100 µl PBS containing 0.2% gelatin and 0.05% sodium azide
Purification method: Protein G purified
This antibody has been succesfully tested for use in following methods: Western blot
Recommended usage: Western blot: 1-3 µg/ml. However, the optimal conditions should be determined individually.
Storage information: Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions: gel pack
How to handle this antibody: The antibody solution should be gently mixed before use.
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation anticorps
Gene targetSIRT7
Short name anti-SIRT7 Antibody
Technique Antibody, anti
Alternative name antibody to-SIRT7 (Antibody to)
Alternative technique antibodies
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