CSB Antibody
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Catalog numberPB10060
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PricePlease ask
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Size0,1 mg
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Target antigenCSB
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ClonalityPolyclonal antibody
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ClonePolyclonal antibody
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Raised inrabbit
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Type of the antibodyIgG polyclonal antibody
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Product formfreeze-dried
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Reacts with specieshuman, rat
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AnalysesWB
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ImmunogenA synthetic peptide corresponding to a sequence at the N-terminus of human CSB (160-205aa QAATSRDINRKLDSVKRQKYNKEQQLKKITAKQKHLQAILGGAEVK).
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Product configurationEach vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
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PurificationImmunogen affinity purified.
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SolubilizationThe powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
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Storage condtionsKeep the CSB Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
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TipsThe CSB Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
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BackgroundDNA excision repair protein ERCC-6 (also CS-B protein) is a protein that in humans is encoded by the ERCC6 gene. This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The encoded protein has ATP-stimulated ATPase activity, interacts with several transcription and excision repair proteins, and may promote complex formation at DNA repair sites. Mutations in this gene are associated with Cockayne syndrome type B and cerebrooculofacioskeletal syndrome 1. Alternative splicing occurs between a splice site from exon 5 of this gene to the 3' splice site upstream of the open reading frame (ORF) of the adjacent gene, piggyback-derived-3, which activates the alternative polyadenylation site downstream of the piggyback-derived-3 ORF. The resulting transcripts encode a fusion protein that shares sequence with the product of each individual gene.
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Related articles1. Muftuoglu M, de Souza-Pinto NC, Dogan A, Aamann M, Stevnsner T, Rybanska I, Kirkali G, Dizdaroglu M, Bohr VA (Apr 2009). "Cockayne syndrome group B protein stimulates repair of formamidopyrimidines by NEIL1 DNA glycosylase". The Journal of Biological Chemistry 284 (14): 9270–9. 2. Troelstra C, van Gool A, de Wit J, Vermeulen W, Bootsma D, Hoeijmakers JH (Dec 1992). "ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes". Cell 71 (6): 939–53.
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Gene NameERCC6
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Protein NameDNA excision repair protein ERCC-6
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Gene Full NameERCC excision repair 6, chromatin remodeling factor
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SynonymsARMD 5 | ARMD5 | CKN 2 | CKN2 | COFS | COFS1 | CSB | ERCC 6 | ERCC6 | RAD26 | UVSS1 | Q03468
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Uniprot IDQ03468
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Entrez GeneID2074
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PropertiesIf you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolMT-CSB1, ERCC6, MT-CSB3, MT-CSB2, CSH2
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Short nameCSB Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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Alternative nameCSB (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namemitochondrially encoded conserved sequence block I
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Synonyms gene
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Synonyms gene name
- conserved sequence block I
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Synonyms
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Locus
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Discovery year1989-10-11
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Pubmed identfication
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Classification
- Mitochondrially encoded regions
Gene info
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Identity
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Gene
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Long gene nameERCC excision repair 6, chromatin remodeling factor
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Synonyms gene
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Synonyms gene name
- excision repair cross-complementing rodent repair deficiency, complementation group 6
- excision repair cross-complementation group 6
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1989-06-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- ERCC excision repair associated
- B-WICH chromatin-remodelling complex subunits
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namemitochondrially encoded conserved sequence block III
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Synonyms gene
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Synonyms gene name
- conserved sequence block III
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Synonyms
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Locus
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Discovery year1989-10-11
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Pubmed identfication
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Classification
- Mitochondrially encoded regions
Gene info
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Identity
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Gene
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Long gene namemitochondrially encoded conserved sequence block II
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Synonyms gene
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Synonyms gene name
- conserved sequence block II
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Synonyms
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Locus
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Discovery year1989-10-11
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Pubmed identfication
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Classification
- Mitochondrially encoded regions
Gene info
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Identity
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Gene
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Long gene namechorionic somatomammotropin hormone 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Growth hormone family
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
