Recombinant Human TIM-3/HAVCR2 (C-Fc-Avi)

• Catalog number
  CU05-10
• Price
  Please ask
• Size
  10 ug

• Description
  Recombinant Human T-Cell Membrane Protein 3 is produced by our Mammalian expression system and the target gene encoding Ser22-Arg200 is expressed with a Fc & Avi tag at the C-terminus.
• Species reactivity
  Human
• Origin
  Human cells
• Peptide sequence
  SEVEYRAEVGQNAYLPCFYTPAAPGNLVPVCWGKGACPVFECGNVVLRTDERDVNYWTSRYWLNGDFRKGDVSLTIENVTLADSGIYCCRIQIPGIMNDEKFNLKLVIKPAKVTPAPTLQRDFTAAFPRMLTTRGHGPAETQTLGSLPDINLTQISTLANELRDSRLANDLRDSGATIRVDDIEGRMDEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKGLNDIFEAQKIEWHE
• Estimated molecular weight
  48.8
• Protein purity
  Greater than 95% as determined by reducing SDS-PAGE.
• Endotoxin level
  Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
• Shipping condition
  Ambient/Room Temperature
• Package form
  Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
• Storage conditions
  Lyophilized protein should be stored at below -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at below -20°C for 3 months.
• Reconstitution conditions
  See included datasheet or contact us for more information.
• UniProt number
  Q8TDQ0
• Other related products
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  TIM-3/HAVCR2   C-Fc-Avi  
• Gene symbol
  HAVCR2, TIMELESS, ARHGEF5, MIR1302-3, MIR509-3, MIR7-3, PIRC14, PIRC12
• Short name
  Recombinant TIM-3/HAVCR2 (C-Fc-Avi)
• Technique
  Recombinant, FC, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Recombinant Human TIM-3 (C-Fc-Avi)
• Alternative technique
  rec
• Alternative to gene target
  hepatitis A virus cellular receptor 2, HAVCR2 and IDBG-55271 and ENSG00000135077 and 84868, protein binding, Plasma membranes, Havcr2 and IDBG-165782 and ENSMUSG00000020399 and 171285

Gene info

• Identity
  HGNC:18437
• Gene
  HAVCR2
• Long gene name
  hepatitis A virus cellular receptor 2
• Synonyms
  • Tim-3
  • TIM3
  • FLJ14428
  • TIMD3
  • CD366
• Synonyms name
  • T-cell immunoglobulin mucin family member 3
• GenBank acession
  • AK027334
• Locus
  5q33.3
• Discovery year
  2002-12-04
• Entrez gene record
  84868
• Pubmed identfication
  • 11823861
• RefSeq identity
  • NM_032782
• Classification
  • V-set domain containing
• VEGA ID
  OTTHUMG00000130249

Gene info

• Identity
  HGNC:11813
• Gene
  TIMELESS
• Long gene name
  timeless circadian regulator
• Synonyms gene name
  • timeless (Drosophila) homolog
  • timeless homolog (Drosophila)
• Synonyms
  • hTIM
  • TIM
  • TIM1
• Synonyms name
  • Tof1 homolog (S. cerevisiae)
  • timeless circadian clock 1
• GenBank acession
  • AF098162
• Locus
  12q13.3
• Discovery year
  1999-01-08
• Entrez gene record
  8914
• Pubmed identfication
  • 9856465
• RefSeq identity
  • NM_003920
• VEGA ID
  OTTHUMG00000170600

Gene info

• Identity
  HGNC:13209
• Gene
  ARHGEF5
• Long gene name
  Rho guanine nucleotide exchange factor 5
• Synonyms gene name
  • Rho guanine nucleotide exchange factor (GEF) 5
• Synonyms
  • TIM
  • TIM1
  • GEF5
  • P60
• Synonyms name
  • transforming immortalized mammary oncogene
  • guanine nucleotide regulatory protein TIM
  • ephexin3
• GenBank acession
  • U02082
• Locus
  7q35
• Discovery year
  2001-02-15
• Entrez gene record
  7984
• Pubmed identfication
  • 8134109
  • 7656213
• RefSeq identity
  • NM_005435
• Classification
  • Dbl family Rho GEFs
• VEGA ID
  OTTHUMG00000158004

Gene info

• Identity
  HGNC:35295
• Gene
  MIR1302-3
• Long gene name
  microRNA 1302-3
• Synonyms gene
  • MIRN1302-3
• Synonyms
  • hsa-mir-1302-3
• Locus
  2q14.1
• Discovery year
  2008-11-03
• Entrez gene record
  100302128
• RefSeq identity
  • NR_031632
• Classification
  • MicroRNA MIR1302 family

Gene info

• Identity
  HGNC:33675
• Gene
  MIR509-3
• Long gene name
  microRNA 509-3
• Synonyms gene
  • MIRN509-3
• Synonyms
  • hsa-mir-509-3
• Locus
  Xq27.3
• Discovery year
  2007-10-24
• Entrez gene record
  100126337
• RefSeq identity
  • NR_030629
• Classification
  • MicroRNA MIR506 family

Gene info

• Identity
  HGNC:31640
• Gene
  MIR7-3
• Long gene name
  microRNA 7-3
• Synonyms gene
  • MIRN7-3
• Synonyms
  • hsa-mir-7-3
• Locus
  19p13.3
• Discovery year
  2004-04-23
• Entrez gene record
  407045
• RefSeq identity
  • NR_029607
• Classification
  • MicroRNA MIR7 family

Gene info

• Identity
  HGNC:37518
• Gene
  PIRC14
• Long gene name
  piwi-interacting RNA cluster 14
• Locus
  3
• Discovery year
  2009-11-05
• Entrez gene record
  100313784
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37516
• Gene
  PIRC12
• Long gene name
  piwi-interacting RNA cluster 12
• Locus
  3
• Discovery year
  2009-11-05
• Entrez gene record
  100313808
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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