NT-4, human recombinant

• Catalog number
  4309-1000
• Price
  Please ask
• Size
  1 mg

• Synonyms
  NT4, NT5, NTF5, NT-4/5, NTF4, Neurotrophin-4, Neutrophic factor 4, Neurotrophin-5, NT-5.
• Alternative_names
  NT4, NT5, NTF5, NT-4/5, NTF4, Neurotrophin-4, Neutrophic factor 4
• Description
  A neurotrophic factor
• Recombinant
  Yes
• Source
  E. coli
• Purity by SDS PAGE
  ≥98%
• Assay
  SDS-PAGE
• Purity
  ≥98%
• Biological activity
  The ED₅₀ as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found in the range of 20-50 ng/ml.
• Results
  20-50 ng/ml.
• Storage Temp
  -20°C
• Shipping
  Gel pack
• Shelf Life
  12 months
• Appearance
  Lyophilized protein
• Physical form description
  Sterile filtered and then lyophilized with no additives
• Reconstitution Instructions
  Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and store at 4°C for 1 week or –20°C for future use.
• Background Information
  Neurotrophin-4 (NT-4/NT-5) is a potent neurotrophic factor that supports the growth and survivability of nerve and/or glial cells. The active form of human NT-4 is a dimer, formed by two identical 130 amino acid subunits.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  NT-4  
• Gene symbol
  NTF4, NTF6A, MIR1302-4, PIRC18, PIRC16, SNORD114-4, MIR941-4, IGKV2OR2-4
• Short name
  NT-4, recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  NT-4, H. sapiens Rec.
• Alternative technique
  rec

Gene info

• Identity
  HGNC:8024
• Gene
  NTF4
• Long gene name
  neurotrophin 4
• Synonyms gene
  • NTF5
• Synonyms gene name
  • neurotrophin 5 (neurotrophin 4/5)
• Synonyms
  • NT-4/5
  • GLC1O
• Synonyms name
  • neurotrophic factor 4
• Locus
  19q13.33
• Discovery year
  1992-10-15
• Entrez gene record
  4909
• Pubmed identfication
  • 1496419
• RefSeq identity
  • NM_006179
• Classification
  • Neurotrophins
• VEGA ID
  OTTHUMG00000191728

Gene info

• Identity
  HGNC:8025
• Gene
  NTF6A
• Long gene name
  neurotrophin 6 alpha (pseudogene)
• Synonyms gene
  • NTF6
• Synonyms
  • PSI-NT4
  • NTF5P
• GenBank acession
  • M86529
• Locus
  19q13.33
• Discovery year
  1992-10-15
• Entrez gene record
  4910
• Pubmed identfication
  • 1496419
  • 1313578
• Classification
  • Neurotrophins
• VEGA ID
  OTTHUMG00000180607

Gene info

• Identity
  HGNC:35296
• Gene
  MIR1302-4
• Long gene name
  microRNA 1302-4
• Synonyms gene
  • MIRN1302-4
• Synonyms
  • hsa-mir-1302-4
• Locus
  2q33.3
• Discovery year
  2008-11-03
• Entrez gene record
  100302130
• RefSeq identity
  • NR_031633
• Classification
  • MicroRNA MIR1302 family

Gene info

• Identity
  HGNC:37522
• Gene
  PIRC18
• Long gene name
  piwi-interacting RNA cluster 18
• Locus
  4
• Discovery year
  2009-11-05
• Entrez gene record
  100313906
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37520
• Gene
  PIRC16
• Long gene name
  piwi-interacting RNA cluster 16
• Locus
  4
• Discovery year
  2009-11-05
• Entrez gene record
  100313849
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:32992
• Gene
  SNORD114-4
• Long gene name
  small nucleolar RNA, C/D box 114-4
• Synonyms
  • 14q(II-4)
• Locus
  14q32.31
• Discovery year
  2006-09-26
• Entrez gene record
  767580
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003196.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:33687
• Gene
  MIR941-4
• Long gene name
  microRNA 941-4
• Synonyms gene
  • MIRN941-4
• Synonyms
  • hsa-mir-941-4
• Locus
  20q13.33
• Discovery year
  2007-10-24
• Entrez gene record
  100126330
• RefSeq identity
  • NR_040032
• Classification
  • MicroRNAs

Gene info

• Identity
  HGNC:5809
• Gene
  IGKV2OR2-4
• Long gene name
  immunoglobulin kappa variable 2/OR2-4 (pseudogene)
• Synonyms gene name
  • immunoglobulin kappa variable 2/OR2-4
  • immunoglobulin kappa variable 2/OR2-4 pseudogene
• Synonyms
  • IGKV2/OR2-4
• GenBank acession
  • X51883
• Locus
  2q11.2
• Discovery year
  2000-04-18
• Entrez gene record
  28858
• Pubmed identfication
  • 2111145
• Classification
  • Immunoglobulin kappa (IGK) orphons

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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