Anti-Catenin, gamma Antibody (11 E4)

• Catalog number
  A1468-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  Catenin gamma
• Target Alternative Name
  ARVD12; Catenin (cadherin-associated protein), gamma 80kDa; Catenin gamma; CTNNG; Desmoplakin III; Desmoplakin-3; DP3; DPIII; Junction Plakoglobin; PDGB; PKGB
• Antibody Type
  Monoclonal
• Clone
  11 E4
• Species Reactivities
  Human, mouse
• Immunogen Sequence
  Recombinant full length human plakoglobin, fused to maltose binding protein
• Accession
  P14923
• Gene Id
  3728
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  In 10 mM PBS with 0.05% BSA & 0.05% azide
• Purification
  Protein A/G purification
• Application
  FC, IF, WB
• Positive Control
  WB: HT20, A549, 293 and A431 Cell Lysates
• Application And Usages
  FC: 0.5-1 ug/1X106 cells, IF: 1-2 ug/ml, WB: 0.5-1ug/ml
• Description
  It recognizes a protein of 80-87kDa, identified as gamma-catenin. The catenins (α, β, γ and δ) are ubiquitously expressed, cytoplasmic proteins that associate with E-cadherin at cellular junctions. Catenin/cadherin complexes play an important role in mediating cellular adhesion. α T-catenin, also referred to as VR22, is a 895-amino acid protein that is most abundantly expressed in cardio-myocytes and in the peritubular myoid cells of the testis. α T-catenin binds to α E-catenin as well as to β-catenin, and it functions to inhibit Wnt signaling. CTNNA3, the gene that encodes for α-T-catenin, is located on chromosome 10, and mutations in this gene show a strong correlation to late-onset Alzheimer s disease (LOAD) as well as to dilated cardiomyopathy.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans
• Handling
  The antibody solution should be gently mixed before use
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Additional description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Catenin   gamma  
• Short name
  Anti-Catenin, gamma Antibody (11 E4)
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Isotype
  Mouse / IgG1, kappa
• Alternative name
  Antibody toCatenin, g (antibody to-) (11 E4)
• Alternative technique
  antibodies

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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