Hippocalcin Antibody, ALEXA FLUOR 488

• Catalog number
  bs-11348R-A488
• Price
  Please ask
• Size
  100ul

• Long name
  Hippocalcin Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
• Also known as
  Anti-Hippocalcin PAb ALEXA FLUOR 488
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 488
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  Hippocalcin
• Specificity
  This is a highly specific antibody against Hippocalcin.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Hippocalcin
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Hippocalcin is a neuron-specific calcium-binding protein found primarily in the plasma membrane of brain and retinal tissue, with increased expression observed in hippocampal pyramidal cells. Through its calcium-dependent signal regulation, hippocalcin can both inhibit rhodopsin kinase and increase phospholipase D2 expression. In order to regulate kinase and phospholipase activity, hippocalcin must bind to the plasma membrane where it can then bind two calcium ions for use in signal regulation. The hippocalcin protein is highly conserved in mouse, rat and human tissue and has a suggested role in neural plasticity and associative memory by contributing to the survival of neurons during aging. The loss of hippocalcin expression is thought to contribute to age-related impairment of post-synaptic functions related to neuronal degradation.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  499nm/519nm
• Synonyms
  BDR 2; BDR2; Calcium binding protein BDR 2; Calcium binding protein BDR2; Calcium-binding protein BDR-2; Hpca; HPCA_HUMAN; Neuron specic calcium binding protein hippocalcin; Neuron specic calcium-binding protein hippocalcin; Neuron-specic calcium-binding protein hippocalcin;P23K.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-Hippocalcin has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor
• French translation
  anticorps

• Gene target
  Hippocalcin  
• Gene symbol
  HPCAL4, HPCA, VSNL1
• Short name
  Anti-Hippocalcin
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 488
• Alternative name
  Hippocalcin Polyclonal Antibody, ALEXA FLUOR 488
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:18212
• Gene
  HPCAL4
• Long gene name
  hippocalcin like 4
• Synonyms
  • HLP4
  • DKFZp761G122
• GenBank acession
  • AB001105
• Locus
  1p34.2
• Discovery year
  2002-05-01
• Entrez gene record
  51440
• Pubmed identfication
  • 10520747
• RefSeq identity
  • NM_016257
• Classification
  • EF-hand domain containing
• VEGA ID
  OTTHUMG00000009246

Gene info

• Identity
  HGNC:5144
• Gene
  HPCA
• Long gene name
  hippocalcin
• Synonyms gene
  • DYT2
• Synonyms gene name
  • dystonia 2, torsion (autosomal recessive)
• GenBank acession
  • BC001777
• Locus
  1p35.1
• Discovery year
  1994-12-14
• Entrez gene record
  3208
• Pubmed identfication
  • 8166736
  • 9931466
  • 25799108
• RefSeq identity
  • NM_002143
• Classification
  • EF-hand domain containing
• VEGA ID
  OTTHUMG00000004017

Gene info

• Identity
  HGNC:12722
• Gene
  VSNL1
• Long gene name
  visinin like 1
• Synonyms
  • VILIP
  • HPCAL3
  • HUVISL1
  • HLP3
  • VILIP-1
• Synonyms name
  • hippocalcin-like protein 3
• Locus
  2p24.2
• Discovery year
  1994-11-02
• Entrez gene record
  7447
• Pubmed identfication
  • 8530085
  • 2202488
• RefSeq identity
  • NM_003385
• Classification
  • EF-hand domain containing
• VEGA ID
  OTTHUMG00000090645

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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