Hippocalcin Antibody, ALEXA FLUOR 555
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Catalog number
bs-11348R-A555
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Price
Please ask
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Size
100ul
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Long name
Hippocalcin Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
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Also known as
Anti-Hippocalcin PAb ALEXA FLUOR 555
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Category
Conjugated Primary Antibodies
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Conjugated with
ALEXA FLUOR® 555
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Host Organism
Rabbit (Oryctolagus cuniculus)
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Target Antigen
Hippocalcin
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Specificity
This is a highly specific antibody against Hippocalcin.
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Modification
Unmodified
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Modification Site
None
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Clonality
Polyclonal
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Clone
Polyclonal antibody
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Concentration
1ug per 1ul
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Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Hippocalcin
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Tested applications
IF(IHC-P)
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Recommended dilutions
IF(IHC-P)(1:50-200)
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Crossreactivity
Human, Mouse, Rat
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Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the antigen
Hippocalcin is a neuron-specific calcium-binding protein found primarily in the plasma membrane of brain and retinal tissue, with increased expression observed in hippocampal pyramidal cells. Through its calcium-dependent signal regulation, hippocalcin can both inhibit rhodopsin kinase and increase phospholipase D2 expression. In order to regulate kinase and phospholipase activity, hippocalcin must bind to the plasma membrane where it can then bind two calcium ions for use in signal regulation. The hippocalcin protein is highly conserved in mouse, rat and human tissue and has a suggested role in neural plasticity and associative memory by contributing to the survival of neurons during aging. The loss of hippocalcin expression is thought to contribute to age-related impairment of post-synaptic functions related to neuronal degradation.
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Purification
Purified by Protein A.
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Storage conditions
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission
553nm/568nm
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Synonyms
BDR 2; BDR2; Calcium binding protein BDR 2; Calcium binding protein BDR2; Calcium-binding protein BDR-2; Hpca; HPCA_HUMAN; Neuron specic calcium binding protein hippocalcin; Neuron specic calcium-binding protein hippocalcin; Neuron-specic calcium-binding protein hippocalcin;P23K.
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Properties
For facs or microscopy Alexa 1 conjugate. Very high photo stable ALEXA conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Conjugation
Alexa Fluor, ALEXA FLUOR 555
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French translation
anticorps
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Gene target
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Gene symbol
HPCAL4, HPCA, VSNL1
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Short name
Anti-Hippocalcin
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Technique
Antibody, antibodies against human proteins, antibodies for
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Isotype
Immunoglobulin G (IgG)
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Label
ALEXA FLUOR 555
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Alternative name
Hippocalcin Polyclonal Antibody, ALEXA FLUOR 555
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Alternative technique
antibodies
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Gene info
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Identity
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Gene
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Long gene name
hippocalcin like 4
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Synonyms
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GenBank acession
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Locus
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Discovery year
2002-05-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- EF-hand domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
hippocalcin
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Synonyms gene
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Synonyms gene name
- dystonia 2, torsion (autosomal recessive)
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GenBank acession
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Locus
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Discovery year
1994-12-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- EF-hand domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
visinin like 1
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Synonyms
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Synonyms name
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Locus
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Discovery year
1994-11-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- EF-hand domain containing
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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