Thrombopoietin, ID (TPO, Megakaryocyte Colony-stimulating Factor, Myeloproliferative Leukemia Virus Oncogene Ligand, C-mpl Ligand, ML, Megakaryocyte Growth And Development Factor, MGDF, THPO)

• Catalog number
  MBS623376
• Price
  Please ask
• Size
  0,2 mL

• Other size
  please contact us to order other different size
• Description
  Colonies can be formed by stimulating factors or recombinant GM-CSF and CSFs activity expressed in Units compared to a standard. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.

• Gene target
  Thrombopoietin   TPO   Megakaryocyte   Colony-stimulating   Factor   Myeloproliferative   Leukemia   Virus   Oncogene   Ligand   C-mpl   Ligand   Megakaryocyte   Growth   Development   Factor   MGDF   THPO  
• Gene symbol
  THPO, TPO
• Short name
  Thrombopoietin, ID (TPO, Megakaryocyte Colony-stimulating Factor, Myeloproliferative Leukemia Virus Oncogene Ligand, C-mpl Ligand, , Megakaryocyte Growth Development Factor, MGDF, THPO)
• Species
  Virus, Viruses
• Alternative name
  Thrombopoietin, ID (TPO, Megakaryocyte Colony-stimulating Factor, Myeloproliferative Leukemia Virus Oncogene Ligand, C-myeloproliferative leukemia virus oncogene Ligand, milliliter, Megakaryocyte Growth And Development Factor, MGDF, thrombopoietin)
• Alternative to gene target
  thrombopoietin, MGDF and MKCSF and ML and MPLLG and THCYT1 and TPO, THPO and IDBG-68171 and ENSG00000090534 and 7066, growth factor activity, Extracellular, Thpo and IDBG-146337 and ENSMUSG00000022847 and 21832, THPO and IDBG-635050 and ENSBTAG00000000476 and 538672
• Virus
  leukemia

Gene info

• Identity
  HGNC:11795
• Gene
  THPO
• Long gene name
  thrombopoietin
• Synonyms gene
  • MGDF
• Synonyms
  • TPO
  • MPLLG
• Synonyms name
  • prepro-thrombopoietin
  • megakaryocyte stimulating factor
  • myeloproliferative leukemia virus oncogene ligand
  • megakaryocyte growth and development factor
  • MPL ligand
  • megakaryocyte colony-stimulating factor
  • c-mpl ligand
  • thrombopoietin nirs variant 1
• Locus
  3q27.1
• Discovery year
  1994-11-04
• Entrez gene record
  7066
• Pubmed identfication
  • 8202154
• RefSeq identity
  • NM_000460
• Classification
  • Receptor ligands
• VEGA ID
  OTTHUMG00000156745
• Locus Specific Databases
  • LRG_580

Gene info

• Identity
  HGNC:12015
• Gene
  TPO
• Long gene name
  thyroid peroxidase
• Synonyms
  • TPX
• Locus
  2p25.3
• Discovery year
  1986-01-01
• Entrez gene record
  7173
• RefSeq identity
  • NM_000547
• Classification
  • Sushi domain containing
• VEGA ID
  OTTHUMG00000090271

MeSH Data

• Name
  Colony-Forming Units Assay
• Concept
  Scope note: A cytologic technique for measuring the functional capacity of stem cells by assaying their activity.
• Tree numbers
  • E01.370.225.500.383
  • E05.200.500.383
  • E05.242.383
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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