anti-HDAC8 (phospho Ser39) Antibody

• Catalog number
  79-160
• Price
  Please ask
• Size
  0.1 mg

• Gene info
  Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by HDAC8 gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.
• Gene names
  HD8, WTS, RPD3, CDA07, CDLS5, MRXS6, HDACL1, MAPKAPK1A, RSK1, HD8, HDA8
• Antibodie s label
  unlabelled serum
• Purity
  Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Spicific to
  This antibody detects endogenous level of HDAC8 only when phosphorylated at serine 39.
• Antigen
  HDAC8 (Phospho-Ser39) antibody was made against a peptide sequence around phosphorylation site of serine 39 (R-A-S (p) -M-V) derived from Human HDAC8.
• Immuno application
  immuno-histo-chemistry, immuno fluorescence
• Antibody advice
  Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
• Suspention pH azide
  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Keep at
  Store antibody at -20 grades C for up to one year.
• Works with
  Human, Mouse, Rat
• Omim nr
  262073088
• Ncbi nr
  NP_001159890.1
• KDa
  42 kDa
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  55869
• GENE symbol
  HDAC8
• Antigene name
  histone deacetylase 8
• Source
  Homo sapiens
• Protein nr
  Q9BY41
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  HDAC8   phospho   Ser39  
• Gene symbol
  HDAC8
• Short name
  anti-HDAC8 (phospho Ser39) Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toHDAC8 (phosphorilated Ser39) (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:13315
• Gene
  HDAC8
• Long gene name
  histone deacetylase 8
• Synonyms gene
  • HDACL1
  • WTS
  • MRXS6
• Synonyms gene name
  • histone deacetylase-like 1
  • Wilson-Turner X-linked mental retardation syndrome
• Synonyms
  • RPD3
  • KDAC8
• GenBank acession
  • AF230097
• Locus
  Xq13.1
• Discovery year
  2000-11-28
• Entrez gene record
  55869
• Pubmed identfication
  • 10756090
  • 10922473
  • 22889856
• RefSeq identity
  • NM_018486
• Classification
  • Histone deacetylases, class I
• VEGA ID
  OTTHUMG00000021814
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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