LSD1 Blocking Peptide

• Catalog number
  33R-10642
• Price
  Please ask
• Size
  50 µg

• Category
  Proteins
• Antibody Subtype
  Blocking Peptides
• Area of research
  Proteases, Inhibitors, & Enzymes
• Type of protein
  Synthetic
• Concentration
  500 ug/ml
• Form Buffer
  Provided in PBS buffer, pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.
• Storage
  Aliquot and store at -20 deg C for short term storage, store at -70 deg C for long term storage
• Shipping conditions
  Blue Ice
• Tested for
  WB
• URL
• More info
• Test
  You can block the antibody by the specific target amino acid sequence of peptide.
• Properties
  blocking peptide
• Gene
  Lysine-specific demethylase 1 (LSD1), the first identified histone demethylase, was belonged to the superfamily of the Flavin adenine dinucleotide (FAD)-dependent amine oxidases. LSD1 specifically demethylates mono- or dimethylated dimethylated histone H3 lysine4 (H3K4) and H3 lysine 9 (H3K9) via a redox process. Recently evidences showed that LSD1 played an important role in a broad spectrum of biological processes, including cell proliferation, adipogenesis, spermatogenesis, chromosome segregation and embryonic development. Furthermore, LSD1 also could promote progress of tumor by inhibiting the tumor suppressor activity of p53. To date, as a potential drug for discovering anti-tumor drugs, the medical significance of LSD1 inhibitors have been greatly appreciated. Here, we reviewed the remarkable progress being made in understanding of LSD1, mainly on its structure, basic function and medical application in tumor therapy.
• Description
  Peptides short amino acid chains or epitopes or blocking antagonists. The shortest peptides are dipeptides, consisting of 2 amino acids joined by a single peptide bond, followed by tripeptides, tetra peptides, ... till polypeptides that are long, continuous, and unbranched synthetic peptide chains. These biological oligomers and polymers can be Solid-phase peptide synthesis (SPPS), or in continue produced for custom peptide synthesis projects. The High-efficiency solid phase peptide synthesis (HE-SPPS) is give very low production costs.

• Gene target
  LSD1  
• Gene symbol
  KDM1A
• Short name
  LSD1 Blocking Peptide
• Technique
  blocking peptide, Blocking, peptide, blocking peptides, fitzgerald made this blocking amino acid sequence or peptide to block the gene target in a volume of 1. For western blot it is often requested to block your antibody and to see the band of the analyzed protein disappear. This is called a negative control by blocking the WB antibody. peptides
• Alternative name
  A synthetic peptide for use as a blocking control in assays to test for specificity of LSD1 antibody, catalog no. 70R-11631
• Alternative technique
  control, peptides

Gene info

• Identity
  HGNC:29079
• Gene
  KDM1A
• Long gene name
  lysine demethylase 1A
• Synonyms gene
  • AOF2
  • KDM1
• Synonyms gene name
  • amine oxidase (flavin containing) domain 2
  • lysine (K)-specific demethylase 1
• Synonyms
  • KIAA0601
  • BHC110
  • LSD1
• Synonyms name
  • Lysine-specific histone demethylase 1A
• GenBank acession
  • AL031428
• Locus
  1p36.12
• Discovery year
  2004-02-26
• Entrez gene record
  23028
• Pubmed identfication
  • 9628581
  • 12493763
• RefSeq identity
  • NM_015013
• Classification
  • MicroRNA protein coding host genes
  • Lysine demethylases
• VEGA ID
  OTTHUMG00000003220

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