Mouse LSD1 antibody
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Catalog number10R-1914
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Price:
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Size100 ul
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ApplicationsELISA, IHC, WB
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Product TypePrimary Antibodies
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Product SubtypeMonoclonal Antibodies
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Research AreaProteases, Inhibitors, & Enzymes
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ImmunogenLSD1 antibody was raised in Mouse using a purified recombinant fragment of human LSD1 expressed in E. coli as the immunogen.
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SpecificityNA
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Cross ReactivityHuman, Mouse, Monkey
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Clone1B2E5
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Concentration1.0 mg/ml
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Form BufferSupplied as a liquid in ascitic fluid containing 0.03% sodium azide.
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StorageStore at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
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Shipping InfoBlue Ice
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PropertiesIf you buy Antibodies supplied by fitzgerald they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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GeneLysine-specific demethylase 1 (LSD1), the first identified histone demethylase, was belonged to the superfamily of the Flavin adenine dinucleotide (FAD)-dependent amine oxidases. LSD1 specifically demethylates mono- or dimethylated dimethylated histone H3 lysine4 (H3K4) and H3 lysine 9 (H3K9) via a redox process. Recently evidences showed that LSD1 played an important role in a broad spectrum of biological processes, including cell proliferation, adipogenesis, spermatogenesis, chromosome segregation and embryonic development. Furthermore, LSD1 also could promote progress of tumor by inhibiting the tumor suppressor activity of p53. To date, as a potential drug for discovering anti-tumor drugs, the medical significance of LSD1 inhibitors have been greatly appreciated. Here, we reviewed the remarkable progress being made in understanding of LSD1, mainly on its structure, basic function and medical application in tumor therapy.
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TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus
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French translationanticorps
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Gene target
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Gene symbolKDM1A
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Short nameMouse LSD1 antibody
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TechniqueAntibody, Mouse, antibodies against human proteins, antibodies for, mouses
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HostMouse
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IsotypeIgG1
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SpeciesMouse, Mouses
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Alternative nameMouse monoclonal LSD1 antibody
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Alternative techniqueantibodies, murine
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Gene info
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Identity
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Gene
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Long gene namelysine demethylase 1A
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Synonyms gene
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Synonyms gene name
- amine oxidase (flavin containing) domain 2
- lysine (K)-specific demethylase 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-02-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MicroRNA protein coding host genes
- Lysine demethylases
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data