ENMD-2076

• Catalog number
  B1938-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  6-(4-methylpiperazin-1-yl)-N-(5-methyl-1H-pyrazol-3-yl)-2-[(E)-2-phenylethenyl]pyrimidin-4-amine
• Description
  ENMD-2076 is a selective inhibitor of Aurora A and Flt3 with IC₅₀ values of 14 and 1.86 nM, respectively. Displays 5-fold selectivity for Aurora A than over Aurora B and less potent to VEGFR2/KDR and VEGFR3, FGFR1 and FGFR2 and PDGFRα.
• CAS Number
  934353-76-1
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₁H₂₅N₇
• Molecular Weight
  375.47
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (~ 18 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A selective inhibitor of Aurora A and Flt3
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  16041424
• PubChem CID Link
• SMILES
  CC1=CC(=NN1)NC2=NC(=NC(=C2)N3CCN(CC3)C)C=CC4=CC=CC=C4
• InChi
  InChI=1S/C21H25N7/c1-16-14-20(26-25-16)23-19-15-21(28-12-10-27(2)11-13-28)24-18(22-19)9-8-17-6-4-3-5-7-17/h3-9,14-15H,10-13H2,1-2H3,(H2,22,23,24,25,26)/b9-8+
• InChi Key
  BLQYVHBZHAISJM-CMDGGOBGSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  ENMD-2076  
• Short name
  ENMD-2076
• Alternative name
  ENMD-2076

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